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hkarargi t1_jeg42yt wrote

Reply to Pardon??? by KLASHINOV

dont worry guys he is just an american spy that was spying on germany for 2 years so he learned the language not your Argentinian grandpa

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TheMightyAndy t1_jeg427b wrote

Reply to What is known about pain enhancement? For instance, are there drugs that are the opposite of analgesics? If so, what are they and how do they work with neurons/neurotransmitters? by DollyPartWithOn

The closest answer would be cytokines. These are proteins secreted by the immune system and basically cause inflammation. Some of these cytokines lower the threshold that pain neurons will start to fire at. This is why touching a part of the body that has been hurt is suddenly painful, where applying the same amount of pressure when the body is healthy would not produce the same response.

There's really not a a lot of indications to make these cytokines into drugs, but one, TNF alpha, has been made into a drug to help ramp up the immune system to fight cancer and has "pain" as a side effect. Most non opiate analgesic's block cytokines in one way or another which is how we get pain relief.

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rimmed t1_jeg4123 wrote

Reply to Margin Call by transformerjay

Margin Call is better for showing what it would have been like in a bank. It also doesn’t show bankers as pantomime villains.

Big Short is a completely different movie. It’s a comedy from the perspective of cynics.

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