Recent comments in /f/askscience
[deleted] t1_j2d32n0 wrote
Reply to comment by [deleted] in How did Rutherford arrive at gold foil as the best choice for his particle experiments? by Poltibolsa
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jrob323 t1_j2d2yst wrote
Reply to comment by keithatcpt in I live in New Hampshire, USA. How come it continues to get colder here after the Winter solstice? by WayneHudsonIII
Yeah there's a 90 degree phase shift as things continue to cool off, like the ocean. But that's also why id didn't start getting immediately cooler after June 21. If you remember, it actually keeps getting hotter and hotter for awhile. The ocean stores it up and starts dumping the heat back into the system in the fall.
[deleted] OP t1_j2d1dto wrote
[deleted] t1_j2d19ux wrote
Reply to Are Educational Video Games Effective? by MEoDP1
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[deleted] t1_j2d0kj7 wrote
menooby OP t1_j2d08lk wrote
Reply to comment by CrateDane in Do human antibodies bind to animal cells? I see that in ANA tests they use rat cells. are they transgenic mice? or just regular mice. by menooby
I see. Thanks again!!
CrateDane t1_j2d05wp wrote
Reply to comment by menooby in Do human antibodies bind to animal cells? I see that in ANA tests they use rat cells. are they transgenic mice? or just regular mice. by menooby
That's describing immunofluorescence microscopy, a more labor-intensive way of doing it. I assume ELISA is more widely used nowadays. And they do mention the option of using human cell lines - that would be the better choice as you want to see if there are antibodies against human nuclear proteins/antigens. Animal cells will have homologous proteins/antigens which some of the antibodies would likely still recognize, but human ones would be better. In an ELISA you would just use purified human proteins/antigens.
[deleted] OP t1_j2czwos wrote
Reply to comment by DetosMarxal in Was there a decrease in other infectious diseases other than Covid due to wearing masks during the past 2 years? by [deleted]
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[deleted] OP t1_j2czmib wrote
shep2105 t1_j2czdzs wrote
Reply to Was there a decrease in other infectious diseases other than Covid due to wearing masks during the past 2 years? by [deleted]
The flu and associated deaths from the flu was virtually wiped out. I never understood the truly ignorant people that kept insisting masks do nothing or that it was some sort of government conspiracy. Especially since I would bet 100% of those people would NOT want a surgeon operating on them with no mask.
That's why we are in the middle of a major flu epidemic. Nobody is wearing masks anymore. You think people would have learned something.
djinbu t1_j2cz7c0 wrote
Reply to comment by shimmeringships in Was there a decrease in other infectious diseases other than Covid due to wearing masks during the past 2 years? by [deleted]
So... In theory... We could dramatically reduce infection rates by making all jobs that could be work at home, work at home? And for those that can't be, rotating working shifts month by month?
harpejjist t1_j2cyxo3 wrote
Reply to Was there a decrease in other infectious diseases other than Covid due to wearing masks during the past 2 years? by [deleted]
Yes. Rates of flu went WAY down in schools last year. (This is in schools where mask and hand sanitizers were the norm) Far fewer absences.
Now I will say that in Dec 2019/Jan 2020 there was a nasty flu going around and a school I work for implemented masks and hand washing/sanitizer regimens. This was before we ever heard of Covid. But for the first time EVER, I didn't get sick, and neither did most students. It was eye-opening. Covid hit just a few months later and we were already totally used to masks and hand washing and so on by then.
People in general but kids in particular now know how to wash hands properly and regularly. School absence rates are lower than expected even now.
menooby OP t1_j2cynkc wrote
Reply to comment by CrateDane in Do human antibodies bind to animal cells? I see that in ANA tests they use rat cells. are they transgenic mice? or just regular mice. by menooby
Wait but they used to use animal cells? https://www.hopkinslupus.org/lupus-tests/lupus-blood-tests/ 'usually sections of rodent liver/kidney or human tissue culture cell lines' What I mean to say is, do human cells and rat cells share the same antigens. Thanks for replying btw
[deleted] OP t1_j2cy9jm wrote
[deleted] OP t1_j2cy7e8 wrote
[deleted] OP t1_j2cy179 wrote
Danzevl t1_j2cxzs6 wrote
Reply to comment by Xyver in Do nerve endings closer to the brain / spinal cord take less time to transmit signals because there is less distance to travel? by ssinatra3
The problem I see there is making an effective organometallic interface or flexible carbon wire that can also send signals back to make it function seamlessly.
[deleted] t1_j2cxnox wrote
[deleted] t1_j2cxijh wrote
CrateDane t1_j2cxa8z wrote
Reply to Do human antibodies bind to animal cells? I see that in ANA tests they use rat cells. are they transgenic mice? or just regular mice. by menooby
The body only really makes antibodies against stuff it has actually encountered. So a human would only have antibodies against animal stuff that has come into contact. Under normal circumstances that might be a bit of hair and the like, rather than more intact/living cells or their nuclei (what ANA tests for).
An ANA test on human blood will usually be ELISA and not have anything to do with animal cells. They will probably use secondary antibodies from some animal (mouse, rat, rabbit, whatever floats your goat) just to bind to and detect human antibodies. You wouldn't be mass producing those antibodies in animals though, rather you'd generate some clonal cell lines.
[deleted] OP t1_j2cx56u wrote
mckulty t1_j2cwzi8 wrote
Reply to comment by neuralbeans in Do nerve endings closer to the brain / spinal cord take less time to transmit signals because there is less distance to travel? by ssinatra3
The difference between nerves that carry light touch and nerves that carry deep pain is pretty big. Remember stubbing your toe and waiting for the pain to arrive?
The difference between a short person and a tall person is not as big as that.
[deleted] t1_j2d34ez wrote
Reply to I live in New Hampshire, USA. How come it continues to get colder here after the Winter solstice? by WayneHudsonIII
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