Recent comments in /f/askscience

djublonskopf t1_j37dihb wrote

In addition to getting out mineral compounds, the soaking helps loosen any clay "dust" that might be left over from firing/shipping. The soak/dry is basically a way of gently washing the pot (and all of its tiny pores) without scrubbing it.

As to the temperature, vegetable oils can even polymerize at room temperature; heat merely speeds up the process. So choosing a low heat like 350° F, and a long time like 2.5 hours, is basically just a "low and slow" way of achieving the same polymerization as a higher heat for a shorter time. However, I suspect that by staying below the smoke point of the oil, you're going to not get that deep black carbonized look associated with cast-iron seasoning, but a much lighter-colored, low-carbonization seasoning that is nevertheless fully polymerized.

As to the choice of oil, olive oil specifically has one of the highest ratios of monounsaturated fats to polyunsaturated fats, so there's fewer carbon bonds available to cross-link for polymerization (meaning polymerization will be slower than with an oil higher in polyunsaturated fats). However, I suspect that u/Corvis_74 is right that the choice of oil is probably not the result of rigorous terracotta-seasoning research.

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Alwayssunnyinarizona t1_j37ci4a wrote

With hepatitis specifically, there is damage to the liver. This causes pain, which can trigger nausea as mentioned, but the liver is responsible for processing various components of the food you're eating (and things like antibiotics or other drugs you might be injected with during an illness). If the liver can't do its job well enough, those components are left unprocessed, which can trigger sensations of nausea in the brain.

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HaveSomeBean t1_j373mo6 wrote

Depends on how religious you are. (/s)

It is technically possible and has been done in labs and extreme cases. No mammal known actively reproduces asexually in nature.

https://en.m.wikipedia.org/wiki/Parthenogenesis#Mammals

The mammal section outlines some cases where it’s happened in lab setting and further below it outlines the basic mechanism

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iayork t1_j373lr0 wrote

There aren’t any natural cases of mammalian parthogenesis, but it’s been done in the lab - with a fair bit of tricky intervention.

> Parthenogenesis, a way of generating offspring solely from unfertilized oocytes, is limited in mammals because of problems arising from genomic imprinting … Parthenogenetic offspring, in which an individual develops from a single unfertilized oocyte, have not been reported in mammals … Here, we report live mammalian offspring derived from single unfertilized oocytes, which was achieved by targeted DNA methylation rewriting of seven imprinting control regions. Oocyte coinjection of catalytically inactive Cas9 (dCas9)-Dnmt3a or dCpf1-Tet1 messenger RNA (mRNA) with single-guide RNAs (sgRNAs) targeting specific regions induced de novo methylation or demethylation, respectively, of the targeted region.

Viable offspring derived from single unfertilized mammalian oocytes

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die_kuestenwache t1_j36z7gg wrote

There is a mechanism called genetic imprinting in higher mammals, which is thought to make the genesis of a fully functional organism without both a full set male and female genes highly unlikely to succeed. It is a topic of ongoing research, whether it is still possible to induce parthogenesis in a lab. It has never been observed in mammals in nature.

[Edit] this took me like 5 minutes to google. But I thought it was so interesting that I summarized it as a thank you for making me learn something today.

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BoilingCold t1_j36z3wt wrote

It's not really known for sure:

"The pain reduction ability of TENS is so far, unconfirmed by sufficient randomized controlled trials. One meta-analysis of several hundred TENS studies concluded that there was a significant overall reduction of pain intensity due to TENS, but there were too few participants and controls to be entirely certain of their validity. Therefore, the authors downgraded their confidence in the results by two levels, to low-certainty. "

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toxicexpectorant t1_j36ktzi wrote

Absolutely it can. Can't give you the scientific explanation but i can all but guarantee that if you let a dishwasher sit for 2 years without any use then try and run it it'll leak like a sieve. Found this to be true with taps as well. A lot of times you go to repair a dishwasher/washing machine and the tap will leak from the stem when you go to turn it off/back on. I think this may be due more to constant pressure on a single point than dryness for the taps if i had to guess though.

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Lepmuru t1_j36hlia wrote

You are 100% accurate with your assessment. The only thing keeping you from understanding is an assumption you made involuntarily (which also is kind of non-trivial).

You select for neomycin-resistance, but not by adding neomycin. Instead, to select eukaryotic cells you would use a substance called geneticin or G418 which is toxic to eukaryotic cells, but cleared by the neomycin-resistance gene.

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