Recent comments in /f/askscience
[deleted] t1_j4728ld wrote
Minute_Farmer t1_j471vtt wrote
There are 4 main types of blood: A, B, AB, and O. Any one of these 4 types can be + or -.
On the surface of the blood cell there are proteins called antigens. The important antigens for this explanation are: A antigen, B antigen, and Rh antigen.
Someone who has A antigens on their blood cells would be type A. Someone who has type B antigens on their blood cells would be type B. If you have both A and B, you're type AB. If you have neither A or B, you have type O.
Rh antigen decides if you're + or -. If you have the Rh antigen, you're +. If you don't, you're -.
So for example, someone with only B antigen and no others would be B-. Someone with A,B, and Rh antigen would be AB+.
The reason it's important to know this is because your body recognizes your cells by recognizing the cell surface antigens on your cells. If a foreign cell surface antigen is detected, your body will attack that cell. So for example, if you have A- blood, you can only recieve a blood donation of O- or A- blood. You can get O- because there's no antigens for your body to recognize as foreign (no B or Rh). In contrast, someone with AB+ blood can receive blood from any blood type, but someone with O- can only receive O-, despite being a universal donor (anyone can receive O- blood.)
Chasethemac t1_j471380 wrote
Reply to comment by 5J7XM33IXN4XCQI6B2BB in What does it mean to torque a screw to a specific torque? by alucemet
Protecting the threads is a huge factor in torque spec.
Material and thread type would determine what you can torque something, too. It's basically the starting point in determining a spec. Valve cover onto aluminum head, for example.
thedeebo t1_j4712wi wrote
Reply to comment by SparseGhostC2C in where does epinephrine comes from? The one used for people with allergies because Google only says It comes from glands so I don't understand if it's donated or sintethized by other means. by SALAMI_21
You don't think there's a profit motive in using all the parts of slaughtered livestock?
PawnWithoutPurpose t1_j470tii wrote
This subject is called pharmacokinetics. How quickly a drug is metabolised and/or cleared from the body. There are various ways to work this out.
I don’t want to say too much here as anything further from me is from memory of a subject I don’t know too much about. But searching pharmacokinetics will give you information on that subject.
It may be worked out in animals, prior to human testing. It could be worked out in the lab via experiments examining enzymatic activity. Metabolism could be worked out by monitoring blood concentrations depending on the drug. Clearance could be worked out by stool, urine monitoring.
It’s a complicated area that I have had maybe two lectures on, so don’t take what I say as gospel
ThatOtherGuy_CA t1_j470iwd wrote
Reply to comment by _AlreadyTaken_ in When nerve damage occurs, where is the pain perceived? at the site of damage or at the end of the nerve? by menooby
Seems like an evolutionary side effect that would normally be beneficial. Pinching a nerve for a prolonged time isn’t good, so when your brain loses feeling to an area it gives you pain signals to trigger you into moving, so that you don’t sleep or sit in a way that could lead to paralysis, and once it gets other feedback it stops.
Unfortunately it can’t tell the difference between a pinched nerve and a lost limb, so it’s instead like “bro move your hand, bro, BRO!!!” And now your left hand that’s been missing for 6 years is suddenly on fire.
[deleted] t1_j470gzr wrote
NiteShdw t1_j470fqu wrote
Reply to comment by [deleted] in What does it mean to torque a screw to a specific torque? by alucemet
I’ve lost screws off my motorcycle because they vibrate out (small ones that hold on the fairings).
[deleted] t1_j4706zd wrote
davidm2232 t1_j470673 wrote
Reply to comment by Different-Truth7668 in What does it mean to torque a screw to a specific torque? by alucemet
>but outright dangerous with alloy rims.
Not true at all. Mechanic/tire shops don't have every customer that had their wheels pulled off come back to have them retorqued. If they are torqued properly initially, no need to retorque.
uwauwa t1_j46zwey wrote
Reply to comment by lucidrage in What does it mean to torque a screw to a specific torque? by alucemet
its due to aluminum allow wheels, something about the softness of the metal "could" loosen after stress cycles.
Different-Truth7668 t1_j46zobq wrote
Reply to comment by davidm2232 in What does it mean to torque a screw to a specific torque? by alucemet
Steel rims deform slightly, giving the connection some "springiness". But alloy wheels don't deform if you stay within the given torque range (if you don't, they crack) so any dirt particles, rust, sand etc. that grinds to dust after initial tightening will leave a gap between the hub and rim.
So forgetting retorque with steel rims is somewhat forgivable, but outright dangerous with alloy rims.
FireTyme t1_j46zlan wrote
Reply to comment by Nago_Jolokio in where does epinephrine comes from? The one used for people with allergies because Google only says It comes from glands so I don't understand if it's donated or sintethized by other means. by SALAMI_21
if anything we've become less efficient at it. in older days we'd use the bones for stock/arrows/tools etc. we'd use the skin for leathers. sinew for string/rope. fat for fuel and preserving and soap. meat and organ meat for food. nowadays we throw most of it out to waste, organ meat barely gets eaten. leather = murder to some people so its used less and less in clothing taken over by much higher environmental impacting synthetic leather. i've spent a project on waste meats for biofuel and theres so much crap that just doesnt get used anymore.
[deleted] t1_j46zhd6 wrote
[deleted] t1_j46z2pd wrote
Reply to comment by Front-Erection in When nerve damage occurs, where is the pain perceived? at the site of damage or at the end of the nerve? by menooby
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[deleted] t1_j46z0mx wrote
Reply to comment by die_kuestenwache in What does it mean to torque a screw to a specific torque? by alucemet
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[deleted] t1_j46yulk wrote
Reply to comment by PLZ_STOP_PMING_TITS in What does it mean to torque a screw to a specific torque? by alucemet
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[deleted] t1_j46ykk5 wrote
[deleted] t1_j46yjx9 wrote
Reply to How do giraffes breathe? by NimishApte
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PLZ_STOP_PMING_TITS t1_j46ygbl wrote
Reply to comment by Scuka1 in What does it mean to torque a screw to a specific torque? by alucemet
If you used a 1 inch long wrench and put 7lbs on it's end would that be equivalent?
[deleted] t1_j46y971 wrote
[deleted] t1_j46xca1 wrote
Reply to comment by Scuka1 in What does it mean to torque a screw to a specific torque? by alucemet
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Front-Erection t1_j46wuu9 wrote
Reply to comment by mckulty in When nerve damage occurs, where is the pain perceived? at the site of damage or at the end of the nerve? by menooby
There are no pain receptors in the body whatsoever. Pain is an experience, a complex output of the mind formed from many various factors, one of which is the input received by nociceptors that effectively detect harmful or potentially harmful change.
That said, neuropathic pain is also somewhat complicated but typically if a nerve is damaged at some point then the pain/altered sensation will follow the course of the nerve from that point to the furthest distal end of the affected nerve.
SparseGhostC2C t1_j472mh5 wrote
Reply to comment by thedeebo in where does epinephrine comes from? The one used for people with allergies because Google only says It comes from glands so I don't understand if it's donated or sintethized by other means. by SALAMI_21
No, I don't. Because I don't know what it takes to process and extract epinephrine from an adrenal gland of livestock, for all I know it's prohibitively expensive to harvest, and maybe the cows need to be raised a certain way for the product to be viable.
There are absolutely industries with manufactured inefficiency for the sake of convenience and profit, I really don't think it's unreasonable just to ask the damn question