Recent comments in /f/askscience

Alwayssunnyinarizona t1_j4jncdx wrote

Reply to comment by [deleted] in Post exposure rabies shots protection? by [deleted]

You'll be at the whim of the county health department I suspect, but it's unlikely you'll have to go through another course if post-exp was less than a month or two ago. Protection lasts a decade or more, but health departments will have different ideas about when post-exp is necessary, and tend to lean towards public safety.

Get the bats taken care of and you'll have less to worry about!

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Alwayssunnyinarizona t1_j4jm35d wrote

Reply to comment by [deleted] in Post exposure rabies shots protection? by [deleted]

Pre-exposure saves you the trouble of immunoglobulin treatment (an often painful subcutaneous injection of several mls) at the site of exposure and 2-3 extra doses of the vaccine series (depending on local regulations).

Source - I've gone through post-exposure (without pre-exposure), and had sufficient titers >10yrs post-treatment.

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Gmn8piTmn t1_j4jjlwq wrote

Reply to How do the new generation of weight loss drugs (Semaglutide, tirzepatide) work and why are they seemingly so effective? by harpoonhambone

Specifically on the stomach the glp-1 receptors on the vagus nerve increase the stretch sensitivity of the stomach which then translates in lower muscle motility and acid secretion.

In the brain it seems to work both directory in indirectly through neuropeptide y and agouti related peptide. NPY is directly implicated with hunger via increase of agouti and also over expression of y is related to emotional (and physical) pain which a lot of people alleviate by over eating

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aliendividedbyzero t1_j4jgwwt wrote

Reply to comment by JimmyJazz1971 in My 4y/o told me her dream about losing teeth without ever knowing it's a common dream. Are there any other examples of cross-cultural phenomena that centers on a specific narrative? by [deleted]

I get the washroom one sometimes! But for me, it's that there's hundreds of stalls. The stalls may have a shower, a toilet, or NOTHING, or for some reason multiple toilets in the same (bigger, like the size of 4 normal stalls put together) stall. If the stall has a toilet and isn't a multiple toilet stall, then it's like really dirty or there's no toilet paper or the door is gone or won't lock or something. There's always something. The usable stalls are always occupied, the ones that would be usable always have someone watching. Worst nightmare.

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PsychoticGiggle t1_j4jdokz wrote

Reply to comment by DukeSuperior_Truth in How do the new generation of weight loss drugs (Semaglutide, tirzepatide) work and why are they seemingly so effective? by harpoonhambone

It definitely works without lifestyle modification, because it still reduces appetite. But all the research has been done on patients that they also promoted lifestyle modification to. And ultimately if someone stops taking the medication hopefully it has helped with lifestyle changes to reduce the amount of weight regained.

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sannerloo t1_j4jbufj wrote

Reply to comment by [deleted] in Post exposure rabies shots protection? by [deleted]

Yes, one reason for taking the PrEP is that many places where you might be exposed to rabies, especially in developing countries, you may not have reliable or safe access to the PEP products so you have more time to get post treatment.

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