Recent comments in /f/askscience

Inb433 t1_j4ytn3j wrote

There’s no evidence that it does anything. David Sinclair is the the one that discovered that altering a protein class called sirtuins can limit aging in yeast. Resveratol works on those proteins. I don’t know of any negative effects to taking it (I don’t think there are but I don’t want to mislead) but there is literally no evidence after a ton of trials that it actually has any effect on anything in humans. The thing is that there are some scientists that are incredibly smart, even among other researchers, and incredibly gifted at designing creative experiments but then draw insane unsupported conclusions from the results.

So basically if you want to take it fine and personally I wouldn’t say I’m completely convinced it’s useless (though it sure looks like it is), but expect it to just do nothing and understand his claims are not backed by his own data.

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Paracelsus19 t1_j4ysh6l wrote

Basically so that we can observe different phenomena and focus on the necessary details in different ways. When your eyes "saccade" - move rapidly from one point of focus to another, our brains are cutting out the information between the two points and just working to rapidly jump from one point of interest to another. With smooth pursuit, our brain and eyes are maintaining a tracking focus on slowly moving target so that we don't miss any detail - if the target speeds up though our eyes will switch to saccade movements to keep up with where the target is going along it's expected trajectory. The video below gives a brief introductory overview of eye movement and will familiarise you with some handy terms to research further.

https://youtu.be/FaC2RXBss2c

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magicfeistybitcoin t1_j4yqtid wrote

Eh. ConsumerLab calls the claims "exaggerated" and "even contradictory." Resveratrol activates the SIRT1 "longevity gene" associated with cellular metabolism, cellular repair, and lifespan. That's where the hype comes from.

The German study they cite re: longevity was small and involved obese mice "on an extremely high fat diet. Whether normally fed mice also show life extension by resveratrol remains unanswered." The high-fat diet mice had a 15% longer lifespan.

A 2017 Denmark study with humans is where the contradictory part comes in. High doses of resveratrol can lead to high total and "bad" LDL cholesterol levels and atherosclerosis. It inhibits an enzyme that metabolizes statins (which affect heart health). Low doses didn't have this effect, but no positive effect was found, either.

The website notes that many clinical studies are currently underway, but their comprehensive examination convinced me not to bother with it right now.

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Andis-x t1_j4yppqv wrote

Your friend is right and then wrong.

Yes, turbocharged engines usually have lower static compression ratio. For example my Subaru had 8.5:1. While NA engine is typically 11 to 13. But why ?

To compensate for higher air pressure from turbocharger. To make more force you need more pressure that comes from explosion. By forcing more air in, you can add more fuel and generate more pressure.

Turbocharged engines tuned for performance need better octane fuel, because you are trying to compress air that is already compressed, meaning that temperature raises more quickly.

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evogytis t1_j4ykq4f wrote

Virus researcher here. The answers provided here cover most of it - the compatibility between virus and host largely determines the success of a virus jumping into a new species. What hasn't been mentioned much is opportunity. There's probably many viruses like SARS-CoV-2 out there in bats and other animals that haven't emerged in humans (yet) because the circumstances that put them in contact with us haven't happened yet. Once they do we'll be at risk of another pandemic. Likewise, many animals are likely susceptible to some human viruses but rarely get a chance to catch them from us.

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