Recent comments in /f/askscience

Lemonyicetea t1_j4zts5t wrote

Absolutely! Despite the Symptoms it's important to remember that you're only considered mentally "sick" if the impairment outweighs your ability to cope with it and live a fulfilling life requiring you to reach out for external help.

If at any point you manage to cope with your initial diagnosis despite the severity of the symptoms and manage to live a happy and fulfilling life you're no longer considered clinically sick.

That's the outcome one would hope when starting a therapy journey.

3

PoopLogg t1_j4ztif9 wrote

> >When cells divide and grow the genetic code isn't copied 100% correctly. There are errors, some get fixed some don't. The ones that don't get fixed and continue to exist are what we call cancer. >

Sometimes it's a cancer, sometimes it's a webbing between your fingers, and that helps you glide when you fall off a tree, and in a million years you're a bat.

9

shitivseen t1_j4ztb9y wrote

They would all be probable causes. Carcinogenicity usually just means that certain substances cause cells to undergo mutations, which could then possibly lead to cancer. However some substances are known to cause specific types of cancer due to the nature of how and where we are exposed to them i.e. skin, lungs, systematic, etc.. Certain chemicals also accumulate in different tissues and would be more likely to cause cancer there. Others get metabolized by the liver and only turn carcinogenic then and there.

1

shitivseen t1_j4zrnbl wrote

To clarify: The vast majority of genetic mutations do not cause cancer. Only when the mutation alters the function of tumor suppressor or pro-oncogenic genes the risk of cancer increases. Additionally there are pathways cells can utilize to prevent cancer development even if a single one mutates. A rule of thumb is that six of these specific genes need to be mutated to actually cause cancer (this can vary of course).

13

Argonated t1_j4zpvse wrote

>The vast majority of black holes have accretion discs, which have such high amounts of hard radiation, any probe would be fried long before it gets anywhere remotely near the black hole.

That's not true. Otherwise they should've been much easier to locate.

>And, using current spaceflight tech, it would take thousands of years to get a probe anywhere near one. So it would be an expensive investment, which might give us useful data in thousands of years.

*Hundreds of thousands

>Besides hard radiation, the only other really cool things we'd want to investigate are either gravitational (we don't have super-tiny gravity sensors to my non-expert knowledge) or quantum in nature (and I don't think we have a particle accelerator we can fit into a space probe.

Aside from the broken English,what¿?

1

No_Ingenuity3366 t1_j4zp51q wrote

Your partly correct only cell devision DNA makes two exact copies that can repear themselves to 100%. When DNA is dammaged by toxic intake true food and environment DNA alters. RNA comes in 3 forms mRNA tRNA and rRNA with each their own fundamental function of the genome translation into practice. However when the genome(DNA) is dammaged the RNA takes over the error and can't fixt it so altered/dammaged proteins get build and altered processes get activated with auto-immuun disease and cancer as a consequence.Genetic mutation is not random it's bonded by toxic environment and ultraviolet light. All chemical elements not from nature in human body (foreign) is toxic and stacksup in organs which leads to disease.

−7

suvlub t1_j4zotz4 wrote

There are actually humans with 44 chromosomes (22 pairs) walking around (typical human has 46 (23 pairs)).

The important thing to note is that these people have the exact same genes as anyone else, they're just organized differently - where other people have (2x)2 chromosomes, they have (2x)1 long fused one. Nothing is missing and nothing is extra, which sets them apart from people suffering from conditions like Down's.

586

FellowConspirator t1_j4zohdz wrote

“Space is big. Really big. You just won't believe how vastly hugely mind-bogglingly big it is. I mean, you may think it's a long way down the road to the chemist, but that's just peanuts to space.” - The Hitchiker’s Guide to the Universe, Douglas Adams

The nearest black hole is 960 light years (5.63e15 miles) away. The fastest spacecraft is the Parker Solar Probe at 430,000 mph. At that speed, it would take 1.22 million years to get the probe there. There’s both technical an economic issues in preparing for a 1.22 million year mission.

1

fruticosa t1_j4zmaji wrote

The "how" is through "chromosomal mutations". These types of mutations occur at the chromosomal level (rather than small, single mutation that happen at the level of the nucleotide). For example, a chromosome can literally break in half at some stage during gametogenesis (the formation of eggs an sperm), turning one chromosome into two.

A common example in plants is through whole genome duplication. A plant starts with two copies of each chromosome, it undergoes some kind of mutation which duplicates all the chromosomes - now the plant has four copies of each chromosome. This is actually how plants (like strawberries) have evolved to become bigger and bigger, they have eight copies of each chromosome.

If some chromosomal duplication occurs, the organism now has redundancy in that it has more copies of each gene than it needs. Over time, the extra genes go through specialisation and evolve to become new genes with different properties (this is how gene families evolve).

223