Recent comments in /f/askscience
HandsOnGeek t1_j50vd2g wrote
Reply to comment by L0cked4fun in Is there any difference in efficacy when a vaccine is administered somewhere other than the upper arm (e.g. on the foot)? by MercurioLeCher
You see that's the thing, the Deltoid is the shoulder muscle. You definitely want the injection into the shoulder, because that is where the Deltoid muscle is. Just, into the muscle, not anywhere else like the joint capsule or whatever.
[deleted] t1_j50v64e wrote
[deleted] t1_j50v0nx wrote
dryingsocks t1_j50u81l wrote
Reply to comment by ceelo71 in Is there any difference in efficacy when a vaccine is administered somewhere other than the upper arm (e.g. on the foot)? by MercurioLeCher
I don't doubt that nurses could do it, but here in Germany vaccinations are administered by doctors, even during the pandemic. Never got one by anyone else
Weed_O_Whirler t1_j50tbgd wrote
Reply to comment by moralprolapse in Whats stopping us from sending a probe into a black hole if we haven't already? by stealth941
The 18 quadrillion is to get out to 1600 light years, as opposed to 100 light years as /u/mfb- is talking about.
Weed_O_Whirler t1_j50t0e7 wrote
Reply to comment by bitwiseshiftleft in Whats stopping us from sending a probe into a black hole if we haven't already? by stealth941
Sorry, I shouldn't have implied there was no interesting science to be done with entangled particles and black holes, I meant to just say there is no way of using entangled particles to get information out of the event horizon of a black hole
HornedDiggitoe t1_j50sxod wrote
Reply to comment by thegreenrobby in Given that reproduction is difficult or impossible when both animals have different numbers of chromosomes, how did so many species evolve to have so many different numbers of them? by MercurioLeCher
> Our knowledge of medicine significantly alters our fitness odds, and allows many genes to reproduce that may not have otherwise survived.
Knowledge of medicine can’t be credited for that. That was largely due to human knowledge of farming/agriculture, as well as human empathy to care for the weak. Humans not surviving long enough to reproduce was historically caused more by a lack of food than anything else. If you had a dead weight (disabled) human in your group and not enough food to go around, guess who isn’t going to get fed?
dkysh t1_j50ssc6 wrote
Reply to comment by JFSOCC in Given that reproduction is difficult or impossible when both animals have different numbers of chromosomes, how did so many species evolve to have so many different numbers of them? by MercurioLeCher
If we were bacteria, yeah, sure. But we are extremely complicated multicellular organisms. A whole genome trisomy screws up the balance of gene expression to such an extreme that most trisomies are simply lethal and never observed (they end up in miscarriage).
A gene fusion is a less drastic event, where 2 chromosomes happen to be connected, but the genetic load is identical.
Weed_O_Whirler t1_j50sb85 wrote
Reply to comment by urzu_seven in Whats stopping us from sending a probe into a black hole if we haven't already? by stealth941
Yeah. I combined "Alpha Centauri" and "Proxima Centauri" in my mind somehow.
etoilech t1_j50s5sb wrote
Reply to comment by L0cked4fun in Is there any difference in efficacy when a vaccine is administered somewhere other than the upper arm (e.g. on the foot)? by MercurioLeCher
Which is why we make people sit down and landmark correctly. Up to 2ml in the deltoid. Find the acromion process and palpate the deltoid. Use the z-track method of injection.
IosaTheInvincible t1_j50rn4q wrote
Reply to comment by SWithnell in Is there any difference in efficacy when a vaccine is administered somewhere other than the upper arm (e.g. on the foot)? by MercurioLeCher
Why IM instead of IV?
ChefArtorias t1_j50rk9e wrote
Reply to comment by UrbanSpartan in Is there any difference in efficacy when a vaccine is administered somewhere other than the upper arm (e.g. on the foot)? by MercurioLeCher
So basically their story is crap is what you're saying?
JFSOCC t1_j50r6a8 wrote
Reply to comment by dkysh in Given that reproduction is difficult or impossible when both animals have different numbers of chromosomes, how did so many species evolve to have so many different numbers of them? by MercurioLeCher
So are people with down syndrome a form of speciation?
[deleted] t1_j50ouy1 wrote
[deleted] t1_j50odo1 wrote
MapleBlood t1_j50od34 wrote
Reply to comment by beezlebub33 in Given that reproduction is difficult or impossible when both animals have different numbers of chromosomes, how did so many species evolve to have so many different numbers of them? by MercurioLeCher
Fascinating, thank you.
firstfrontiers t1_j50ntmt wrote
Reply to comment by Roadgoddess in Is there any difference in efficacy when a vaccine is administered somewhere other than the upper arm (e.g. on the foot)? by MercurioLeCher
There's overlap between medications and some medications can be given either way. However IM is going to be a slower release over time versus being immediately introduced all at once into the bloodstream. I know the form of medication or the substance it comes in plays a role too, some play better with different tissue types (some meds we give into the fat tissue as well depending on absorption). There's also the issue of bleeding risk which would be higher trying to give something IV when it's safer in a clinic setting to just give it IM. But as far as I'm aware the biggest factor is the more controlled release time
Dro-Darsha t1_j50nokv wrote
Reply to comment by Sylvurphlame in Given that reproduction is difficult or impossible when both animals have different numbers of chromosomes, how did so many species evolve to have so many different numbers of them? by MercurioLeCher
It’s not enough to have one or few viable offspring though. Also they have no good way to find each other, so they need to be able to reproduce with the other chromosome count until they reach a critical number
stickymaplesyrup t1_j50nlvg wrote
Reply to comment by suvlub in Given that reproduction is difficult or impossible when both animals have different numbers of chromosomes, how did so many species evolve to have so many different numbers of them? by MercurioLeCher
Okay, hear me out.
One of the ways we define whether or not species are different is if they can reproduce together, and if the offspring are also able to reproduce. This is why horses and donkeys are still different species even though they can have babies, ie mules, because mules are sterile.
What if these 44 chromosome people grew in number and could have kids together (non-incestuously, I don't know if there are multiple families with this condition)? And then those kids could have kids, and so on.
Would this be the origin of a new species of human?
It's fun to think about and consider.
[deleted] t1_j50ni7q wrote
Reply to comment by [deleted] in Is there any difference in efficacy when a vaccine is administered somewhere other than the upper arm (e.g. on the foot)? by MercurioLeCher
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Moldy_Teapot t1_j50ndyl wrote
Reply to comment by Silverjeyjey44 in Is there any difference in efficacy when a vaccine is administered somewhere other than the upper arm (e.g. on the foot)? by MercurioLeCher
I can't speak to how it would affect the vaccine and the body's response to it, but I can say that giving a vaccine Intravenously is impractical and potentially dangerous at scale. I work in an ER and it can easily take 20+ minutes to start an IV on a patient, especially if they're very young or very old. That's compared to administering Intramuscularly which will take 2 or 3 minutes at most. From what research we've done on vaccines, doing it intramuscularly is perfectly fine so there's just no reason to change that. There's also a greater risk of sepsis going from IM to IV since you're opening a path directly into your bloodstream instead of just near it (again I can't speak to whether or not the vaccine itself would cause issues, but I can't imagine it would help).
[deleted] OP t1_j50n1p4 wrote
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smnms t1_j50vf70 wrote
Reply to How is protein folding quantum mechanical? by prionprion
Quantum mechanics explains the orbitals of an atom's electrons, and also the molecular orbitals of covalent bonds between atoms. Orbitals are also important for the van-der-Waals forces, hydrogen bonds, and interactions with the molecular orbitals of surrounding water molecules, which direct protein shape.
In the end, all chemistry is applied quantum mechanics, and protein folding is chemistry.