Recent comments in /f/askscience
bruce_kwillis t1_j6fftgi wrote
Reply to comment by mohirl in Can you (roughly) determine the dosage of a drug taken based off of the blood concentration? by bynarie
Correct.
OP is asking the wrong question. Based on what day provided it seems in line with an overdose, especially with the other drugs involved, unless the person was a known addict.
From a tox report you only have a snapshot at the one particular time point. You need multiple time points to even potentially guess the starting dose along with an extensive patient history.
momoneymocats1 t1_j6ffrnc wrote
Reply to comment by TRJF in Can you (roughly) determine the dosage of a drug taken based off of the blood concentration? by bynarie
In other words, they explain a drugs pharmacokinetics and pharmacodynamics
atomfullerene t1_j6ff1vy wrote
Usually what's going on is that genes determine how a plant will respond to those various other factors. And growing fruit from seed you get a crazy grab bag of genetics.
DeepCompote t1_j6feust wrote
Reply to comment by tswd in When you have a sun tan and it fades what is actually happening? by Immediate_Rough_7661
So I got a sunburn this summer. The lines on the top of my legs were very bright. The line on my left leg is still visible. How long is a skin cell life cycle?
[deleted] t1_j6fe9bd wrote
Reply to comment by [deleted] in When our eyes are adjusting to new light levels, what are they actually doing besides dilating the pupil? by Ryan949
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supagirl277 t1_j6fe74n wrote
Reply to Can you (roughly) determine the dosage of a drug taken based off of the blood concentration? by bynarie
They do this to make sure the serum is the right level in people who take medications that can change levels based on how long you take it. You need a base number to go off of, so there’s no way to tell exactly how much someone took, but if you’ve tested every month, you’ll know how much that amount will look like in their blood over time. You can tell if someone has overdosed when there’s an amount far greater than a normal dose has entered the system, since it is not longer in the safe therapeutic range and has likely done some damage
[deleted] t1_j6fdcrf wrote
Reply to comment by divariv in Can you (roughly) determine the dosage of a drug taken based off of the blood concentration? by bynarie
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mohirl t1_j6fd26g wrote
Reply to comment by [deleted] in Can you (roughly) determine the dosage of a drug taken based off of the blood concentration? by bynarie
Surely time is a large factor?
[deleted] t1_j6fcyx2 wrote
[deleted] t1_j6fcnso wrote
Reply to comment by FelisCantabrigiensis in How much truth is there in the idea of avalanches being started by loud noises? by Mammoth-Corner
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Optimistic__Elephant t1_j6fcjaq wrote
Reply to comment by TheRedLob in Can you (roughly) determine the dosage of a drug taken based off of the blood concentration? by bynarie
Somewhat relatedly, how come prescription medicine isn’t sized based on the patient weight?
[deleted] t1_j6fchsd wrote
Reply to comment by [deleted] in When our eyes are adjusting to new light levels, what are they actually doing besides dilating the pupil? by Ryan949
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[deleted] t1_j6fch94 wrote
Reply to comment by TRJF in Can you (roughly) determine the dosage of a drug taken based off of the blood concentration? by bynarie
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[deleted] t1_j6favyt wrote
Reply to comment by divariv in Can you (roughly) determine the dosage of a drug taken based off of the blood concentration? by bynarie
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[deleted] t1_j6fagse wrote
FelisCantabrigiensis t1_j6f9lmn wrote
Reply to How much truth is there in the idea of avalanches being started by loud noises? by Mammoth-Corner
100% truth.
Cannon firing explosive shells, or hand-held explosives, are used to trigger avalanches deliberately to reduce risk to people moving in mountainous areas with heavy snow.
You didn't ask how loud a noise. The answer is "very loud" - explosions. Yelling loudly won't do it.
[deleted] t1_j6f8xul wrote
[deleted] t1_j6f8qub wrote
[deleted] t1_j6f4sxq wrote
Reply to comment by girnigoe in Why can an adult’s GI tract expel C. botulinum spores while an infant can’t? by curiousnboredd
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AquaSlothNC t1_j6f4sms wrote
Reply to comment by The-fire-guy in Why can an adult’s GI tract expel C. botulinum spores while an infant can’t? by curiousnboredd
No not at all! I appreciate the catch and you're totally right. I used the wrong term and had meant germination, not sporulation. Its been awhile since i've had to think about this lifecycle. Sorry about that! I've corrected my previous posts and used 'germinate' where applicable.
[deleted] t1_j6f1bue wrote
Reply to comment by pathoj3nn in Why can an adult’s GI tract expel C. botulinum spores while an infant can’t? by curiousnboredd
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The-fire-guy t1_j6f0qk5 wrote
Reply to comment by AquaSlothNC in Why can an adult’s GI tract expel C. botulinum spores while an infant can’t? by curiousnboredd
Just to clarify, I wasn't trying to be snippy, I appreciate the information either way. But are you using "sporulate" here to mean "becoming active"? Isn't it the other way around?
If not, how is the bacterium going dormant an issue if it has already entered the body?
[deleted] t1_j6f0bvr wrote
ic3man211 t1_j6ey0ua wrote
Reply to comment by GoldenMegaStaff in Can you (roughly) determine the dosage of a drug taken based off of the blood concentration? by bynarie
Op is describing a case where someone has committed a crime and the police are determining if the amount of drug in their system at the time is abnormally high and would have caused some issues…not like the offender would volunteer they took too much of their painkiller and drove into oncoming traffic
hypatia_knows_best t1_j6fhib9 wrote
Reply to comment by azuth89 in What makes it difficult to determine whether nutrient deficiencies are implicated in mental-health issues like ADHD? by LinguisticsTurtle
Actually many studies show linkages between advanced paternal ages and ADHD, autism and schizophrenia.