Recent comments in /f/askscience

silent_cat t1_jady8y2 wrote

Well, there are all sorts of genetic abnormalities that cause genetic males to appear female. But none that cause genetic females to appear as male.

Sure, there are any number of hormonal triggers, but if you miss all of them you appear female. Note, it's the appearance that relevant, because with these various syndromes they still tend to have testes rather than ovaries. It appears that the signal to produce a penis however requires an actual on signal.

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DeismAccountant OP t1_jadwsa6 wrote

As I said, I generally accept the range of 380-780nm (although I hope to see experiments on expanded human vision in the future) as the limits of wavelength when building the axis opposite to irradiance, and 555nm is all the site gave me.

For now I’m hoping I can find a way to trace a feasible range on the chart in the last page.

Your comment is appreciated. I know someone else left a reply but I think they’re shadowbanned?

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Coomb t1_jadwjsm wrote

Reply to comment by Taxoro in How old is the ISS REALLY? by gwplayer1

The satellites do get their internal clocks updated by the control segment fairly regularly, but you're right that the reason isn't the accumulation of the relativistic error.

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lazercheesecake t1_jadvkqt wrote

That there is an epigenetic component is not what was contentious. My point being it is unknown which mechanism in the temperature-signal pathway is the root of TSD. KDM6B is proven to be a vital component in the epigenetic expression of DMRT1 but what triggers KDM6B? That is unexplained.

Also, I do admit "in humans, all babies start off development as females." is a bit of an exaggeration, but it is not incorrect. As seen in AIS individuals, as I highlighted in my post, without male differentiating hormones, human bodies, for the most part, develop phenotypically into female presenting bodies. So much so that prior to modern times and ready genotyping, the most common diagnoses of AIS occurred in mid to late puberty when the individual did not start menses or develop other secondary sex characteristics.

Many male organs are direct descendants/adaptations of female organs, the differentiation of which occurs only in the presence of male differentiation hormones.

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