Nope. I can only see 4 top-level comments, including mine.

i've reposted the comment and deleted the original lmk if you see it now

What is a therapeutic index (TI for short):

TI is a way of gauging a substance toxicity. It can be calculated in two different ways:

• LD50 / ED50
• TD50 / ED50

LD50: lethal dose in 50% of the test population

ED50: dose to achieve desired effects (in this case experiencing pyschoactivity) in 50% of the test population

TD50: dose to experience toxic effect in 50% of the test population

​

In this case all the values are calculated using the first method.

Keep in mind that the substances used are pure and in a lab environment.

Addressing inaccuracies:

As you might imagine calculating the TI of a given substance for humans is pretty hard, this data is based on animal studies and estimates based on death reports, so it might not be incredibly accurate. Also the therapeutic index calculated this way doen't directly measure how toxic a substance is for your body, although a broad therapeutic index generally implies a less toxic substance.

(?): since it's unknown if these substances can cause death in humans it's really hard to calculate their TI

(*): LD50 are all over the place for this substances, this is the best i could find.

Sources: https://pdfhost.io/v/Tdx47N5.G_TI_of_various_drugs

Tool: google sheets

if you find more accurate sources please link them in the comment's

edit: some clarifications

When I actually think about this, it is so depressing. these products are so overvalued and people are undervalued. :/

The Tory’s have consistently cut spending, then point to the NHS failing to garner support for their ultimate plan. Privatisation.

Truly evil.

wtf, this is wierd

[deleted]

One is a teoretical value and the other is true money that goes round in a economy on the yearly basis.

Dude, I can't see it at all. Clicking on your link takes me to "Wow, so empty" page.

Specifically wanted to highlight this graph, real terms underspend and no wonder we are in a crisis with Nurses striking and others considering it too.

That’s just it. It DOESNT show how massive apples market cap is via a comparison for perspective because the comparison is invalid.

It just shows apples market cap and then a separate number next to it. No perspectives obtained from a comparison.

it's easier to overdose on it (it's still incredibly hard)

edit: i've read your comment wrong lol, you can overdose more easily on caffeine, lsd is completely bodily safe.

New bar chart idea

Number of laughs from reading comments dunking on the ludicrous comparison on this chart

Vs

Number of insightful wisdoms gleaned from the chart

dude i've done the comment: https://www.reddit.com/r/dataisbeautiful/comments/10532eh/oc_estimated_toxicity_of_various_common_drugs/j38gbe3?utm_medium=android_app&utm_source=share&context=3

It makes more sense to compare Apple to oranges

[removed]

[deleted]

Next you might as well compare the number of iPhones manufactured to the GDP of these countries.

Why are we comparing market cap to GDP?

More (Less is Worse)

This is a very odd comparison. It's similar to compare someone's net worth to someone else's yearly salary, doesn't really make sense. One is accumulated wealth over time, the other is how much they make in given year.

I guess Senegal do love their XBOX

it's like comparing how many knots are in a string to how many knots is a boat doing

Since the OP haven't provided sources and explanations in the comments, here we go:

Therapeutic index isn't the same as toxicity. It describes how easy it is to 'overdose' and and used to measure how safe a drug is in terms of dosage.

What is doesn't describe is how much damage a drug can make to a body, how severe side-effects may be or how quickly you can become dependent on the drug.

Nah, we should take Apple and distribute the money to these countries.