I sure do love the 4Kids Evangelion spoof.

Sorry to ask so much but we’re learning lots here.

Ketamine is a new one for me in terms of chronic pain. You remain conscious, like it’s a low dose?

I’ve never done intravenous acetaminophen plus an NSAID so I could see that being much better than oral potentially.

How often can you do nerve blocks and what’s the longest they last like half a day?

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Dudes on reddit who make $15/hr, own nothing, and are perpetually lonely: "Yeah bro, women are basically banging down my door to take half of my fortune."

Sorry this is not beautiful, this hurts my eyes!

Y-axis is completely random to make things fit...

You’re good I was just looping it back into the conversation which is opioid replacements. And yes I only emphasize side effects because the drastic severities for example dementia later in life versus some tiny weight loss or gain.

Shrugs I just know that would be something along the lines dubbing studios here in the states have done. 4Kids instantly comes to mind.

Spend all their budget on dubbing all these projects and putting together new opening songs, only to save a few bucks by using the same pool of voice actors they already had on speed dial.

You do realise that each percent could be represented with a different shade, right? Just like the rainbow isn’t exactly 7 colors

You’ve never heard of Beverly Hills?

Correct in that it would be great if we had more drugs to choose from and yes, like all drugs they all have side effects, pros and cons and are situational. No drug is perfect.

Plus I listed analgesics because that is what someone asked for a list of but I didn't mean that all are suitable for chronic pain. Very little is. In fact the best therapies often aren't pharmaceutical for chronic pain.

R.e. steroid side effects they include increase in glucose levels, reduction in immune system response, a decrease in endogenous steroid production, increaser risk of GI bleeding and weight gain/hunger. Very unlikely to get these from a single injection like your friend though and actually it's unclear why single shot steroids remain so effective for as long as they sometimes do.

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Best example why not to get married and make as many prenups as possible

This data anonymizes the tree’s age. Pretty complicated algorithmic stuff to perform, big win for the privacy buffs out there.

And u/Liuk7

Ah, that explains it.

Wrong. If you have a foot amputated I can block the pain completely with a nerve block of just 20mls of local anaesthetic in the correct locations. Or I can give you ketamine and your pain is no longer an issue.

Similarly I know patients who cry out with their pains and they are on 160mg of morphine twice a day with extra opioid doses in between. Blatantly if they are crying out, the opioid are nit effective.

I've anaesthetised patients for operations, given them 20mg morphine and they are still in severe pain in recovery. Then you give them some IV paracetamol and diclofenac and the pain goes from 10/10 to them happy and chatting.

It all depends on the situation.

So…. Its rank order, just as the comment asked

Good list but yeah very situational. Also I do not know if I am an outlier but unless I have swelling I do not take NSAIDs and acetaminophen has never done much in my experience. Maybe it helped with one headache in my life haha. Tylenol liver issues and NSAID issues but they make special formulas for longer term use now (coated to not harm GI).

Gabapentinoids maybe but it has its own side effects - might not be great for neurology long term like most things though I guess but might be more pronounced in a drug like pregabalin (neuroplasticity).

Clonodine and fluoxetine don’t seem very light either not to bash them if they work great for someone and they do not mind side effects.

Local anesthesia seems to have some serious draw backs from my quick read and makes sense why I haven’t heard of it more.

I’ve known someone who had back pain from like a pinched nerve in a herniated disk get a steroid shot that lasts a long time but I don’t know how many situations that can be applied to and what steroid side effects are like.

Alcohol seems a bit meh to suggest as chronic pain reliever and magnesium seems like a long shot but if it works I’m glad for those people. I do not use pain medicine or have had issues with chronic pain so I do not mean to bash the list but yeah we are in desperate need for drugs that produce analgesia or block pain like opioids do.

Both Adnan Khashoggi and Alec Wildenstein were owners of Ol Pejeta ranch in Kenya at different times (Adnan sold it to Alec and his wife Jocelyn transformed it into a luxury camp in the 1990s got perhaps cat obsession there).

Adnan bought stuff in Kenya from another billionaire... Tiny Rowland owner of Lonrho and friend of Al-Fayed. I think Al Fayed bank rolled Adnan.

Ol Pejeta is still owned by an anonymous billionaire (Wildensteins sold it) who turned it into a conservancy owned/run by a trust.

Adnan also bought Mt. Kenya Safari Club and turned it into a billionaires nest (place where Jack made first ever tweet from Kenya about 2009)

Bill Gates bought an Island last month in Malindi close to the property of Flavio Briatore, an Italian Billionaire who lives in Kenya and bought Naomi Campbell's her home (now a resort) in Kenya.

Bill Gates though is not alone Richard Branson owns stuff in Kenya too and has a popular camp resort inside Maasai Mara. Coincidentally Bill Gates loves the Mara, he camped there for new years 31st December 1999 with his then young family.

Seems billionaires like to flock. Where there is one there is plenty of others even though it doesn't seem they even interact in anyway. In places like Kenya no less.

There are others but like to be more discreet.

The first actually positive critic in the comments! Finally, thank you!

Mediaset/Berlusconi. Berlusconi's TVs had a massive role in importing and popularise anime in Italy (and other European countries, like in Spain), and the company responsible for the recording of the songs was owned by Berlusconi as well. So she simply worked for a single company that distributed hundreds of animated series. Mediaset even produced several albums with the theme songs from animated series https://i.discogs.com/LyMJAWm9_zjQl_o97lOogZv2NG1CsMLN5nItCM6VHuY/rs:fit/g:sm/q:90/h:350/w:350/czM6Ly9kaXNjb2dz/LWRhdGFiYXNlLWlt/YWdlcy9SLTU1NTY1/NzktMTM5NjQ2MTQ1/NC03OTAyLmpwZWc.jpeg

0+20/2=10

So the avrage is 10% in the lowest colour, I think using a very pale green colour is actually better, then just white. Probably every state has sone forest area.

I mean, you can tell the différence between them. We've seen worse shit

I had a look, I think the figure is very wrong and is a statement of how much money was on the table at the time - their combined wealth being the $2.7b.

From what I can see, it would appear, following his Yeezey brand disaster, she is both far more liquid than he is, but her net worth is now about $300m or so more than his.

I think they have split their $75m shared assets, the only agreement beyond this is his $166,000 per month per child payments, at $199,200 per annum. There is no spouse support

I think Kim's quite unfairly included in this list as, unlike others on here (I promise this isn't meant to as sexist, the theory would work identically if I included a wealthy woman and her husband - think J.K. Rowling and her husband - a doctor - divorcing), Kim was independently very wealthy (circa $ 750m), she has seemingly accepted a split of their joint owned assets, child support and joint custody.

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I think it's because she was the one doing most of the openings for the biggest tv network in italy (mediaset) which also had the most stuff for kids/teenagers so she ended up doing so many anime.

Animes that were bought by other channels have different singers if they adapted the opening eg some of the most famous probably are fist of the north star and saint seiya.