Recent comments in /f/explainlikeimfive

Ansuz07 t1_j2dvj9o wrote

There are small muscles attached to each hair follicle. When those muscles contract, the skin tightens up and the hair stands on end. When they relax, the bump goes away.

As for why they are still there, evolution doesn't have a goal - it rewards what works. There was never a benefit in the reaction going away, so it never did.

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NobblyNobody t1_j2dva92 wrote

but what's the actual mechanism?

something in the follicles?, muscular, or fluid moving around? why does the skin feel tighter? where does whatever the bumps are made of go afterwards, why didn't that mechanism go when we lost the hair - does it serve another purpose most of the time?

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cookerg t1_j2dv2dk wrote

There is no "whole time". When you take a medicine, a certain portion of it gets into your blood stream and permeates your body. Immediately your liver and other body parts start deactivating and removing it. If the half life is 12 hours, then at 12 hours half of it is gone, so you are down to 50% of the peak level. In another 12 hours, you are down to 25%, then 12.5%, and after about 5 half lives, so little is left we consider it pretty much gone, but trace amounts actually remain in your body for longer.

It's also useful to know that if you keep taking the drug, let's say for a condition like epilepsy where you need a constant minimum amount of drug in the body, at first it starts to accumulate in your body as you are adding more drug before the previous dose is cleared, and it takes about 5 half lives before you reach a steady state or plateau, where the blood level is the same every day. It still shoots up to a peak after each dose, and then drops somewhat before the next dose, but the peaks and valleys are the same every day at steady state, so you can be confident that even at the lower blood level just before each dose, there's enough drug to prevent seizures.

Half life is also useful to know if you stop a drug, because you know that in about 5 half lives it'll be pretty much gone.

Sometimes half life can change due to some other drug or medical condition, and that is useful to know as it may mean you have to adjust the dose of your drug to correct for that. In overdoses, sometimes the mechanisms that clear drugs from the body can't scale up to deal with high drug levels, and the half life is longer and it takes longer than expected to recover.

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DrewsBag t1_j2duydg wrote

Don’t listen to the commies on here. Yes, we do. The billionaires wealth is tied up in stock ownership. Usually, when their wealth goes up, it’s because the general stock market is gaining value. Those is us who have our retirements tied up in the same stock market, want the stock value to go up. Also, a growing market also indicates a good economy, which pushes wages and work opportunities. The bullshit about ‘fair share of taxes’ is a red herring.

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constantino675 t1_j2dusma wrote

You're half right. The biggest contributor to dulling is mineral deposits from drying cycles.

If you dry the blade after every use (including a blast of compressed air) the blades can last 150+ shaves with minimal wear.

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Pandalite t1_j2dun7z wrote

Even shorter- you know how a cat puffs out its hair when it's scared or cold? Humans do the same thing except we're not furry like that anymore.

More info:

There are little muscles in hair follicles that make them stand up. It's called piloerection. It's controlled by the sympathetic nervous system.

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angrybird7677 t1_j2duhip wrote

When u are thinking a thought, do you feel the thought forms in your head or in other parts of your body? For me at least, I imagined myself having the thoughts coming through from my head... Perhaps I was brainwashed into learning that the brain is in my skull, therefore the thought comes from there? Hence my preconceived notion?

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AnotherManDown t1_j2duhia wrote

The jury is still out. Despite our advancements and accomplishments we know astonishingly little about human consciousness, and how exactly is it that organic chemistry can produce a being that perceives, thinks, dreams and produces unbelievable achievements in every way imaginable.

But first things first, let's check the language we're using. Whereas the brain is a physical organ situated inside the skull, the mind is an abstraction. What we call "the mind" is actually a set of functions - our capacity to perceive, analyze, dream up and influence reality (there is probably a more comprehensive way to describe it, but I'm shooting from the hip here). My point being that "the mind" is a roof term not an observable object.

It's still a very useful term and I don't want to downplay it in the least, but, almost paradoxically, it only exists inside the mind via language.

Now whether our thoughts and dreams are produced inside our brains and we all make up our own minds (pun intended), or whether the brain is more akin to a receiver-broadcaster that channels the mind, is a matter of opinion, not fact. There's no evidence to support either, and science usually picks the more conservative estimate, whereas spiritualism is more liberal. But they both know exactly the same amount, which is almost nothing.

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Bawstahn123 t1_j2dtmyw wrote

>A century ago, the original treatment on Europe was hot herbs/lemon liquors (diluted in water) and sweet wines, which also comes with a few extra "side effects".

Aka "grog" or "a hot toddy"

Spirit of your choice. Whisky or Rum is "traditional", but any "brown liquor" would be ok

Tea, black, made hot, almost boiling

Lemon juice

Sugar of some kind. Honey is my usual go-to, but maple syrup was an interesting substitute.

Spices. I like cinnamon and ginger

Make the tea, and while very hot, add everything else.

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TeamGrissini t1_j2dteco wrote

For some reason my mother used to have a large bottle of codeine as cough medicine at all times (in the 1990s), and I had it quite often. It's not great for chesty coughs, though, as it stops you from coughing the stuff up and out of your system.

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