It’s like someone who comes into your house and eats your food and breaks your stuff and hides your bills. At first it doesn’t have a huge impact but eventually your power is cut off because you haven’t paid your bills, you have no food to eat so you are starving, you can’t properly rest because all your furniture is broken… cancer starts by just consuming the resources in your body, and it becomes overwhelming. It spreads to other areas and does the same thing.

It is so dangerous because your immune system doesn’t recognise it because it’s starts as your own cells. So with the person in your house metaphor, it’s someone dressed up like a family member so you let them in, you don’t throw them out even when you know there is a problem because you assume it’s not them that’s causing the problem.

Advanced cancer treatments function by ‘tagging’ the cancer as an enemy so your immune system fights it. But many treatments just try to kill everything in the radius of the cancer, while trying to limit damage to the rest of your body. So again with the house metaphor - you know the problem is in the corner of one room so you basically try to destroy that area without hurting the rest of the house too much. But there is still damage to the structure of the house that has to be repaired afterwards. This is why cancer treatments are so rough, You basically are killing off your own cells too, just trying to kill the cancer faster so that you can have time to recover.

To add to everyone else talking about logistics network efficiency, stores have a metric for ‘days of inventory’ in the building. It adds up the price of everything they have, and subtracts an average day of sales until the store hits 0.

For most grocery stores, the number is somewhere between 6 and 10. A big box store might push the number to 14.

If they stopped getting trucks today, your local grocery store is probably empty in a week.

Cool. I didn't know that.

Damn. You live in an urban area or outside the US? Assuming it is Flashfood (one word) app, it doesn’t look like any store does that in my area. Shame, I would love to buy discounted uglies.

Masters degrees are not usually pre-requisites for doctorates. They are often two entirely different programs and application processes. Everyone I know with PhD’s both in science, tech and humanities went directly from undergraduate degree to doctoral programs.

ETA: I’m responding from a US perspective as apparently this isn’t the case globally.

ELI5

You go ask your next door neighbor to borrow $20 to fill up your gas tank to get to work. You've lived next to your neighbor for 10 years, and he knows you're pretty responsible, so he lends you the money. He trusts you.

But you find yourself short on gas next week too, and you don't want to bug your neighbor again, so you ask the mailman. Now, the mailman doesn't know anything about you, so he's got no reason to trust you.

But you tell the mailman, "Hey, go talk to my neighbor, he knows me really well, and I've paid him back many times, he'll tell you that you can trust me".

And so the mailman does this, and now he trusts you to repay the money.

It's the same thing on a bigger scale. You have a credit card. You pay your amount off every month, you never carry a balance. If you open a second credit card, the first credit card can now VOUCH for you. They will say "astajaznan pays off every month, he's trustworthy with money".

The same is true with car loans. If you pay your monthly payment every month without issue, then the bank will VOUCH for you if you want to get another car loan down the road.

The same is true for mortgages. And other lines of credit (where you are given money up front, with the expectation you pay it back).

If you're behind on some car payments, that lowers your trustworthiness. If you are always at your credit limit on your credit card, that lowers your trustworthiness.

Banks look at your trustworthiness to determine whether to loan you more money. Banks look at your trustworthiness to determine what interest rate you will have to pay when repaying a mortgage.

So ALL these institutions (car loan bank, credit card, mortgage bank) release all their information about your trustworthiness, to some central catalog. The central catalog keeps track of everyone's trustworthiness.

The central catalog has to "rate" your trustworthiness. You could do it on a scale of 1-10, or one to four stars, but they chose some other rating, that goes up to like 800.

That rating, that single number, is your credit score.

Now all banks have a easy way to tell, from a single number, whether it's risky to loan you money.

YES, PEOPLE, it's a lot more complicated than that. But this is ELI5, and this gets the job done.

PhD stands for doctorate of philosophy. It’s an abbreviation, not an acronym.

It depends. I know at my store they look at numbers from the previous year to predict how much we need that day; a lot of food gets thrown out but if a manager is keeping things tight there’s not as much food waste as you’d think, probably.

Like, not saying there isn’t a lot of waste; but at when it comes to fresh meat and seafood it really depends on the manager in charge and the predictions from the previous year. Like the meat all comes in vacuum sealed or ordered in expectation of the sale week; most seafood comes in frozen and the fresh stuff is ordered specifically for the sales week - there’s also the stuff corporate just wants in the case because it looks good even if it doesn’t sell like live shellfish or lamb. I’m sure it matters store by store, but I know my store for example doesnt move much seafood. So that’s our biggest waste; I think most people (I don’t live near the coast or a big river/lake) aren’t as comfortable dealing with seafood as they are red meat.

See my other response.

But also think that there are all sorts of reasons planes crash, and all sorts of planes. A plane crashing at a large airport often does not significantly slow air traffic outside that directly impaired by the use of that runway or airport, depending on severity.

This might help you understand what the levels of education and understanding look like

We called it Just in time inventory. Looked at historical movement while taking account for out of stock inventory. Our goal wasn't to have maximum possible stock, but enough stock as it's needed. That way we didn't carry excessive inventory, just what we would need when we needed it.

Some does go bad, but it’s actually a very small amount. Mid single digits for perishable, a fraction of that for shelf-stable. There’s not as much product on shelves as you think, relative to the number of people buying it. So you might see only a couple of people buying a particular product in the store while you’re there, but that’s happening constantly throughout the week.

One thing to know, is that in most stores there’s not product “in the back”. What you see on the shelf is what they have until the next truck comes, so they have to keep it stocked. That’s also why when everyone in a 2 mile radius decides they need toilet paper at the same time, it runs out in a hurry.

Fuck yrah

Not many are explaining the actual difference beyond what order you get them, though they did a good job of explaining order and whatnot.

Undergraduate degrees (most often 4 year programs that you see in TV and that most people "going to college" get) are a broad overview of a field. Someone who finishes is by no means an expert, but is ready to be trained on-the-job in their field. A biology major may have taken a class on animals which makes them ready to work in a zoo, where they will use their knowledge to help learn more job-specific information.

There are other degrees like associate's degrees, and those are usually a very in-depth job training (not the best way of describing). Or it's half of a bachelor's degree in a different field, most would not recommend this.

Graduate school typically narrows the focus of your studies, and typically makes you do a thesis (a large project or piece of work that takes one or more years to complete). After graduate school you become an expert in your field. Someone from the zoo would call you because you are an expert in animal digestive systems and our undergraduate, capable as they are, doesn't know what to do.

There are professional degrees as well, teachers get a 'professional' masters as do some other professions (social work, pastors, mental health professionals) the difference being that instead of a big project, they essentially do an internship.

There are also law and medical school, which are graduate programs where you learn to do law and medicine.

I assume you are from America. In our country (in the Balkans), a completely different logic prevails. Although I believe that this principle will come to life in our country at some point, since we follow the trends, and America is always light years ahead of us.

Here's a case where there might be a change in the odds. Usually, after a crash, there's a period of increased vigilance by ground crews to be on the look out for maintenance issues and speeding up checks of various systems. It's almost certainly safer to fly in the weeks following a high-profile crash.

I think your math is off on calories per day per pound of muscle. My muscle mass is about 85 lbs and I definitely am not burning 12,000 calories a day.

Thanks I just edited it. I assume that's my error and not some recent change.

If you keep putting small pebbels into a straw, eventually the first pebbles will start to come out the other end.. it’s not the one you put in last that comes out first, but they are connected. The reason that the feces might be different if you, for example, eat a huge meal, is because your body will now try to make room for that new food, while the old food it now tries to get rid of, isn’t fully processed

This. The odds of rolling 6 6s in a row are pretty n low (like less than 1/1000). But once you've rolled 5 6s in a row the odds that the next one will be a 6 are 1/6.

Probability only looks forward

Fastest way to stop is to lock your wheels up with ABS turned off. ABS doesn’t make you stop faster, it just improves steering as you brake. It sacrifices a tiny amount of braking for that control. ABS would help Keep the rubber side down though which is nice. A car skids farther on its roof. Engine breaking doesn’t do anything if your wheels are already locked up.

For a motorcycle which can tip over easier, abs is definitely going to keep the rubber on the road better. Note: I’m not suggesting that anyone turn ABS off. But if it was a competition to see who could drop fastest, and all identical cars, those who used the least ABS would win.

It's because cancer cells break off of the original cancer and then spread throughout the body. This causes growths in vital organs like the brain or liver or lungs etc and will cause them to fail as they grow and you die. Usually, doctors will check the lymph nodes closest to the original cancer as lymph nodes filter bacteria/infection and broken off cancer cells as they pass through them. If you have cancer in the lymph nodes closest to the original cancer site then you can tell that some cells have broken off and started to spread throughout the body.

Leukemia is a cancer of the body's blood forming tissue, it causes an overproduction of white blood cells.

I'm aware of that but OP specifically used the term "vertical stabliizer", which excludes fuselage-mounted tail engines.

Credit scores can now go above 800. I'm not sure when they changed that, tho.

Source: i just bought a car and had an 840 something.

Yes, I somewhat understand. But isn't someone who doesn't use credit cards and manages to cover all their expenses with their income the safest for the bank?