Recent comments in /f/science
Tykjen t1_j7ysfqh wrote
Reply to New find of Stone Age tools dated 300k years earlier than previously thought, 2.9 million years ago, along with butchered hippos and human-like ancestors by qartas
Human history just keeps getting older. Awesome.
AutoModerator t1_j7ysejw wrote
Reply to The discovery of fossils dating back 250.8 million years near the Guizhou region of China suggests that complex ecosystems were present on Earth just one million years after the Permian-Triassic mass extinction, which is much earlier than previously thought. by Wagamaga
Welcome to r/science! This is a heavily moderated subreddit in order to keep the discussion on science. However, we recognize that many people want to discuss how they feel the research relates to their own personal lives, so to give people a space to do that, personal anecdotes are allowed as responses to this comment. Any anecdotal comments elsewhere in the discussion will be removed and our normal comment rules apply to all other comments.
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Sgt_Munkey t1_j7yq5vp wrote
Reply to According to a study on 12,211 patients, aspirin is just as effective at preventing blood clots as low molecular weight heparin, but it costs less and is easier to administer by giuliomagnifico
Just recovering from a smashed ankle and have to inject dalteparin daily. I hate needles, and wish this was prescribed instead... Perhaps it may be useful for a period of time when my lmwh course ends if I'm still stuck in bed elevating my leg...
mrsmoose123 t1_j7yose3 wrote
Reply to Analysis: Cannabis Products Mitigate Need for Other Prescription Medications in Chronic Pain Patients by GivenAllTheFucksSry
Reflects my experience. I feel very lucky, but also annoyed that the NHS was paying for the medications I've come off, but I have to pay for the cannabis.
[deleted] t1_j7ylb0n wrote
Paul_C t1_j7ykdu2 wrote
Reply to comment by charonpdx in Analysis: Cannabis Products Mitigate Need for Other Prescription Medications in Chronic Pain Patients by GivenAllTheFucksSry
There's a pubmed link to it in the first sentence of the article.
Chesterlespaul t1_j7yhis0 wrote
Reply to comment by Protonoto in Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial (Feb 2023) by basmwklz
These are facts. Consider it a challenge and you are doing it for a good reason, helps motivate ya. In the end, a little hunger isn’t going to kill ya… at least not for many many days.
AutoModerator t1_j7yft36 wrote
Reply to Following extensive electrochemical performance experiments, a research team has found a specific composition that could open doors to high-performance magnesium rechargeable batteries. Substituted magnesium-vanadium systems could eventually lead to the much awaited next-generation batteries. by rustoo
Welcome to r/science! This is a heavily moderated subreddit in order to keep the discussion on science. However, we recognize that many people want to discuss how they feel the research relates to their own personal lives, so to give people a space to do that, personal anecdotes are allowed as responses to this comment. Any anecdotal comments elsewhere in the discussion will be removed and our normal comment rules apply to all other comments.
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YepYep123 t1_j7yfg7i wrote
Reply to According to a study on 12,211 patients, aspirin is just as effective at preventing blood clots as low molecular weight heparin, but it costs less and is easier to administer by giuliomagnifico
It’s important to look at what they define as their primary outcome.
Aspirin was non-inferior to LMWH when it came to death from any cause. However, the rates of venous thrombosis (which is what ASA and LMWH are trying to prevent) was higher in the aspirin group. It was only 0.8% higher, though in a study of over 12 000 patients that equates to an extra 1000 people getting a blood clot and this was statistically significant.
While these blood clots may not have increased mortality, that doesn’t mean they have no morbidity. Patients can get chronic symptoms of swelling and pain after a DVT (called post thrombotic syndrome). This is reported in around 20-50% of patients with DVT, so conservitavely 200 people on the study are likely to have long term symptoms (often lifelong) as a result of being randomized to aspirin. While more rare, there is also risk of cardiac and lung complications after a pulmonary embolism (such as pulmonary hypertension) which can be quite severe.
At my hospital, nearly all patients are on LMWH for VTE prevention and complications from this are exceedingly rare. If it were me in hospital with a fracture, I’d take LMWH over ASA any day.
Source: Hematologist who sees people on blood thinners every working day.
AnnexBlaster t1_j7yevf3 wrote
Reply to comment by BuggerMyElbow in According to a study on 12,211 patients, aspirin is just as effective at preventing blood clots as low molecular weight heparin, but it costs less and is easier to administer by giuliomagnifico
Theres proteins in Staph aureus called clumping factors which active platelets, and pore forming exotoxins called alpha hemolysins which cause major damage.
Sepeis varies a great deal between bacteria, the toxins from different pathogens determine whether your immune system will win, or how fast and painful your death will be
megapighead t1_j7ycw35 wrote
Reply to comment by Pleasant__Bumblebee in Researchers Block Allergic Reactions to Peanuts in Mice – In an important first step to protect against peanut allergies in humans, researchers used a first-in-class allergen-specific inhibitor to prevent allergic reactions in humanized mouse models. by swhelan_tn
I relate to this so much. I also have a severe peanut allergy, can't go anywhere without some level of anxiety.
Protonoto t1_j7ycgec wrote
Reply to comment by AloneDay8829 in Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial (Feb 2023) by basmwklz
try a fast, your body gets used to it quickly and you stop feeling hungry so easily
AloneDay8829 t1_j7ya1os wrote
Reply to comment by SeanyfaceYCG in Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial (Feb 2023) by basmwklz
I feel crappy if I don't eat very much though.
dumbest_smartass t1_j7y7u8b wrote
Reply to Analysis: Cannabis Products Mitigate Need for Other Prescription Medications in Chronic Pain Patients by GivenAllTheFucksSry
:( I miss the pain meds that work best for me. Mmj made life manageable. Especially parenthood as a single parent, it made my chronic pain almost nonexistent with the presence of my child. (Never consumed in the same vicinity or while child was awake or able to smell or see it, before the mombies and other undesirables try piping in.)
BuggerMyElbow t1_j7y68tl wrote
Reply to comment by AnnexBlaster in According to a study on 12,211 patients, aspirin is just as effective at preventing blood clots as low molecular weight heparin, but it costs less and is easier to administer by giuliomagnifico
What are the toxins involved in sepsis and where do they come from?
I'd imagine they come from the bacteria, so lipopolysaccharides/endotoxin? Are these responsible for platelet malfunction?
Also how does sepsis vary depending on the species and strain of bacteria?
epelle9 t1_j7y5ia4 wrote
Reply to comment by zero0n3 in Researchers find that outdoor cannabis can "express more cannabinoids with potentially desirable bioactivity" compared to cannabis cultivated indoors under artificial lights. by OregonTripleBeam
Well, no studies are perfect, but if thats the soil they are grown when sold, it makes sense to compare them that way, and is definitely useful data.
[deleted] t1_j7y59ez wrote
Reply to comment by charonpdx in Analysis: Cannabis Products Mitigate Need for Other Prescription Medications in Chronic Pain Patients by GivenAllTheFucksSry
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charonpdx t1_j7y570a wrote
Reply to Analysis: Cannabis Products Mitigate Need for Other Prescription Medications in Chronic Pain Patients by GivenAllTheFucksSry
FFS, people. I don't object to posting studies that show the actual medically-beneficial aspects of cannabis - but at least post the links to the actual study, not to obviously-biased sources' summaries/news articles of it...
[deleted] t1_j7y52xp wrote
AutoModerator t1_j7y526u wrote
Reply to Analysis: Cannabis Products Mitigate Need for Other Prescription Medications in Chronic Pain Patients by GivenAllTheFucksSry
Welcome to r/science! This is a heavily moderated subreddit in order to keep the discussion on science. However, we recognize that many people want to discuss how they feel the research relates to their own personal lives, so to give people a space to do that, personal anecdotes are allowed as responses to this comment. Any anecdotal comments elsewhere in the discussion will be removed and our normal comment rules apply to all other comments.
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zero0n3 t1_j7y4y29 wrote
Reply to comment by ohgoshyes in Researchers find that outdoor cannabis can "express more cannabinoids with potentially desirable bioactivity" compared to cannabis cultivated indoors under artificial lights. by OregonTripleBeam
CMH bulbs were designed by the military for subs and replicate the wavelengths used by the sun.
Here’s some old but accurate info: https://migrolight.com/blogs/grow-light-news/grow-light-spectrum-explained
zero0n3 t1_j7y4jbb wrote
Reply to comment by epelle9 in Researchers find that outdoor cannabis can "express more cannabinoids with potentially desirable bioactivity" compared to cannabis cultivated indoors under artificial lights. by OregonTripleBeam
Except you then don’t know if it was actually outdoors that led to this or say the nutrient mix lacking some ingredient in the indoor mix.
It’s useless data.
zero0n3 t1_j7y4e5b wrote
Reply to comment by A_Swayze in Researchers find that outdoor cannabis can "express more cannabinoids with potentially desirable bioactivity" compared to cannabis cultivated indoors under artificial lights. by OregonTripleBeam
Also what light did they use indoors as a test? HPS? CMH? MH? some LED hood?
Wagamaga OP t1_j7ysg2f wrote
Reply to The discovery of fossils dating back 250.8 million years near the Guizhou region of China suggests that complex ecosystems were present on Earth just one million years after the Permian-Triassic mass extinction, which is much earlier than previously thought. by Wagamaga
About 250 million years ago, the Permian-Triassic mass extinction killed over 80 per cent of the planet's species. In the aftermath, scientists believe that life on earth was dominated by simple species for up to 10 million years before more complex ecosystems could evolve. Now this longstanding theory is being challenged by a team of international researchers – including scientists from McGill University and Université du Québec à Montréal.
A fossilized ocean ecosystem Until now, scientists have long theorized that scorching hot ocean conditions resulting from catastrophic climate change prevented the development of complex life after the mass extinction. This idea is based on geochemical evidence of ocean conditions at the time. Now the discovery of fossils dating back 250.8 million years near the Guizhou region of China suggests that complex ecosystems were present on Earth just one million years after the Permian-Triassic mass extinction, which is much earlier than previously thought
https://www.science.org/doi/10.1126/science.adf1622