Depending on where they lived, they could have frozen meat or dried meat to preserve it, and you can smoke meat anywhere if you build something to trap the smoke in around the fire. If there’s a party to hunt and kill the elephant the party can all chip in to preserve it.

And air conditioning

It is very clear, now that large-scale studies are being done on the use of cannabis since the 1st legalisations in 2016, that the prohibition of this herb is solely due to the industries that knew they would suffer with cannabis legalisation.

There was a previous study here which stated that for every $1 spent on cannabis, upto $0.80 is not spent on alcohol. And now this study, which shows that cannabis is being substituted for dozens of costly pharma medications as in "65 percent ceased their use of opioids, 60 percent stopped using antidepressants, and 58 percent ceased their use of anticonvulsants".

The alcohol and pharma industries are not stupid and would have done their own internal studies which would have showed exactly this; that cannabis will threaten their profit margins. And they would have doubled down on the fear-mongering and lobbying politicians to continue to demonise the herb.

But this in no way exonerates the public from blindly and ignorantly accepting the lies and corruption. How long ago did we find out that corporations act based on profits, and politicians act based on re-election? The morality of the society must come from us.

There is no such word as "identficating". The word you are looking for is "identifying".

And let me just say that this is a big pet peeve of mine. That is when people replace -ing suffix in participle verbs with -cating which does not exist and just sounds ignorant.

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It's not a straw man, my point was that diet is not monitored in most of these studies as was noted in the study you linked and even when diet is monitored, it is still not equal because fiber is used to supplement the diets of the animals eating the calorie restricted diet, therefore the diets are not equal in nutritional value. There's more to a good diet than low amounts of highly processed foods as I noted in a different comment, a low amount of consumed animal products along with a good amount of fiber and adequate consumption of all essential amino acids, proteins, fats, carbs, vitamins and minerals is also needed.

There has not been a study that has established why caloric restriction results in increased health and longevity therefore we can't say that it's not the co-factors associated with caloric restriction (i.e., better diets, intermittent fasting, fasting correlated with circadian rhythms, etc.) that are primarily responsible for the beneficial effects rather than the restriction of calories itself.

My purpose in pointing out blue zone diets was to demonstrate that health and longevity do not require caloric restriction. My point was also to demonstrate that caloric restriction leads to hunger and hunger leads to impaired mood and cognition which has also been well documented in other studies. Caloric restriction has benefits but we can reap those benefits through a good diet, without restricting calories, without going hungry, and without affecting our mood and cognitive abilities.

Most likely not identifiable as human by modern standards.

I do not dispute that fiber has health promoting benefits. I do feel that it’s a bit of a straw man from the original point, though. The discussion seemed to be that the less processed food, in the blue zones, was responsible for increases in longevity, independent from CI. From that perspective, I believe the animal studies, where diet composition is the same (degree of processing isn’t different) and CI is the IV, are useful. I believe they provide evidence that energy intake affects longevity independent processed food consumption.

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Drug Companies don’t like cannabis because they don’t make enough money on it. They pay for the propaganda so they can get you to take experimental drugs that don’t work. I’ve tried all kinds of mood stabilizers.. nothing works better than a little bud at the end of the day.

Not a case study, just bad heart/blood pressure issues. She's already had one stroke and two stents. She has A-fib and damage to one of her ventricles from an "undiagnosed" heart attack. (It wasn't diagnosed as a heart attack and she didn't have any symptoms of a heart attack, but she has damage that's evidence of a heart attack.) So they're trying to keep her heart from over working itself, trying to keep her arteries from clogging any worse, while trying to keep the stents from throwing any more clots while also not overwhelming her kidneys and liver.

So she's on a low dose of three blood thinners for the time being to try and protect her heart and lungs and eyes from further damage without destroying her kidneys.

I am writing my thesis on this exact topic currently and I wanted to say this exact thing. We roughly know that dopamine is released in these areas as a response to reward/reward predicting stimuli and that dopamine is also involved in a lot of regulatory activity. We know it affects cordination, motivation, emotion regulation etc etc. Knowing this and then thinking about what is the best way to fix a dopamine misfunction (If there is one?, May not be the case) are two seperate things ESPECIALLY, when this system responds to SOOO many different forms of stimuli. Currently I would say a holistic approach (Lifestyle changes, therapy, maybe a medicinal treatment aswell (ie. Methylphenidate (Ritalin) seem to be potential approaches to look at). Deciding what is the best and why and for who is really hard

yes but hypermesis when the pot is too potent

Are they Wall Street mice in little business suits sniffing cocaine and yelling "Sell! Sell!" Into their phones?

Since the "opioid crisis" MMJ can be the only thing a lot of us chronic pain patients get... but it's not the same. It should be use as an addition, but not as a substitution, for legit pain managment. It can be very good for other symptom management tho!

No no, the world was created like 4000 years ago, after the Egyptian civilization had already thrived for a thousand years. /crazyligious people

It's amazing how far back we go, and how fast things start changing with innovation. First it takes a million years to master one thing, then a million for another, and then suddenly only a few thousand years, and then 10k years ago explosion and that just keeps giving.

Although things like monotheistic religions are really slowing down society in this regard.

I think big pharma has the resources...and influence to do whatever they want

Yeah but it’s a huge obstacle to navigate. Federal laws, state laws, who will control it? Is it even an FDA or USDA? It’s a plant yeah? Lot to work through for what might lose them money.

Because there are truckloads of cash in a nascent market

This is largely a pro marijuana subreddit.

The nucleus accumbens and prefrontal cortex (the structures identified in this study) have been shown to be involved in reward and drug addiction for decades, but we still don't have treatments.

Sewing machines. We invented sewing machines.

If it's any part of the reward system it could be a really good target.

It could be. If further studies prove that the activation causes the behavior. On the other hand, if the behavior causes the activation or the brain region activation and the drug-seeking-behavior are both caused by some third, unmeasured variable, then this has no treatment value.

As I said, correlations are valuable. Mis-representing them is not.