Recent comments in /f/science

FwibbFwibb t1_j8y4imc wrote

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randerton1 t1_j8y3gh8 wrote

Whoops - sorry - should have clarified. I meant any additional studies that validate this statement. This statement defies common sense from those of us in the real world who are surrounded by Covid victims of all age groups who have shown no long Covid symptoms 3 months after initial infection.

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vwb2022 t1_j8y0zo0 wrote

20 years ago when I was doing my PhD I became friends with a bunch of climatologists as our offices were next to each other. Their view was that the model is always lagging behind, because we first need to observe the effect to include it into the model.

So whatever the model is telling us, the things will get worse faster than that. If the model is saying that 2 degC increase is safe, that's probably not true and we should aim for 1.5. We already burned through 1 degC increase, so things are not looking good.

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teddy_002 t1_j8xxlnb wrote

believing in god doesn’t inherently mean you believe god has the power to affect your physical health.

it’s also sad when people perpetuate stereotypes about religion through ignorance.

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peer-reviewed-myopia t1_j8xwm8t wrote

I don't understand the value of this research. Depression has been known to correlate with memory dysfunction and decreased hippocampal volume. 5-HT4 (serotonin 4) receptors have been known to be involved with memory, and the structural plasticity effects within the hippocampus.

However, compared to other serotonin receptors, the function of 5-HT4 throughout the brain and periphery is diverse and complex — which makes sense when considering how relatively large / complicated the gene encoding 5-HT4 is, and how little is known about the regulation of its transcription.

There is strong evidence regarding the involvement of 5-HT4 in depression, but imaging that quantifies global reductions is completely insufficient. Humans show different responses in 5-HT4R expression in different brain regions. SSRIs have been shown to decrease global 5-HT4 binding. Depressed suicide victims show increased 5-HT4 receptor binding in the caudate nucleus and frontal cortex.

This study has zero value in paving the way for new drugs.

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MRSN4P t1_j8xrobb wrote

Very interesting. This begs the question of whether serotonin impacting medications (SSRIs, etc) affect memory performance in people with and without depression.

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