Recent comments in /f/science

Archaris t1_j8yz0iw wrote

> rising demand

limited demand... from what? a return to pre-pandemic production levels? The production was always there (no missing refineries afaik) they just have a few convenient reasons to gouge everyone unable to negotiate fair prices.

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pete_68 t1_j8yw8k2 wrote

This seems silly. Of course dogs are going to match our actions more than a wolf. Dogs evolved to be likeable to us. That's how they got rewarded with food. The ones who do things we liked got rewarded with food and were more fit to survive and breed. 130,000 years of that and food is no longer required as the reward. They've evolved to want to please us.

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atchijov t1_j8yw7tf wrote

At the very least this is the small part of the problem… record profits posted by every single fossil fuel related company is much bigger issue. Russian war is just a convenient excuse.

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Michaelcycle13 t1_j8yu7yq wrote

Haha we're saying the same thing about the commensal bacteria aspect. I never did say that commensal bacteria activated the T cells as you so put. I'd love to hear more from you. I'm a Long Covid struggler who's on the mend. A lot of people don't know what is going on, medical professionals especially, however, everyone has their theories.

I think through discourse like this we're only going to improve in knowledge and learn more. Obviously I do not have a background in immunology as you say you have. I've also been looking into starting a Long Covid Collaboratory podcast where we bring in other people struggling to share stories, share what helped us, and discuss symptoms. Would you ever be interested in saying some words?

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bannedPosts t1_j8ytvrk wrote

There's no explanation - aside from wishful thinking - SSRIs do not work any better than placebo. In fact, the most reliable predictor of efficacy is believing they will work. If your doc can sell it, it might work. Sounds like religion to me. If, and I say if, SSRIs worked as advertises they would work in a few days not months / years. No other class of drugs enjoys more apologists than SSRIs.

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Penis_Envy_Peter t1_j8yto4t wrote

It's unfortunate, but not surprising, that people in a world of pain cling to outlandish ideas. You can even reach the conclusion that suffering is good, as the article suggests the subject did.

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discotititis t1_j8ysyeh wrote

I’m on mobile so pardon my formatting.

> The body’s bacteria along with antibodies find and detect its existence.

This is not true. Yes, there have been some studies that show that commensal bacteria are important for signaling to T cells. However, they do not activate T cells. T cell activation only occurs upon recognition of an antigenic peptide presented upon the MHC molecule of a dendritic cell in the lymph node. Signaling from commensal bacteria only has an effect once T cell activation occurs, when it can affect the differentiation of a T cell down different lineages. T cells can only then activate B cells, which produce antibodies. Antibodies for previously unknown viruses do not exist in the body yet—that’s why it takes so long to mount an immune response because it takes some time for a T cell with the correct receptor to recognize the virus as presented on a dendritic cell.

The initial recognition of a virus, though, occurs from innate immune cells that can recognize patterns present in lots of viruses. In response, these innate immune cells produce cytokines that begin the process of inflammation and activate dendritic cells to take up virus and travel to the thymus. These cytokines can affect the differentiation of T cells down different lineages (killer, helper types 1, 2, and 17, regulatory, follicular). These cytokines also affect the type of antibody produced, as different antibodies have different properties for better neutralizing different kinds of microbes.

Notice how the thymus isn’t involved in any of this. It’s very important but it doesn’t really play a role in the basics of the immune response.

I really wouldn’t rely off random internet doctors for immunology research, sorry. Way too many conspiracy theorists online. Research papers are also going to be way too advanced at this stage. Sompayrac is your best bet. I’ll even sell you my copy. Even Cells at Work (on Netflix) is going to be more accurate and helpful.

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Uturuncu t1_j8yswjq wrote

Anecdotally as an adult with autism and not epilepsy, I was prescribed lamotrigine for mood stabilization in conjuction with antidepressants. My mood was more even(antidepressants chopped the bottoms off the lows, but everything was still a neurlogical roller coaster; lamotrigine addition turned it into a kiddy coaster with smaller valleys and shorter peaks instead of a thrill seeker's death trap) so it worked for that... But it did nothing at all for autism symptoms, no.

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TomSwirly t1_j8yrcze wrote

You use communism like a three-year-old uses the word "poo-poo" except that three-year-old actually understands the meanings of the word she is using.

It is impossible ever to have any sort of adult conversation about these matters when giggling and deliberately ignorant simpletons spent all their time screaming lies and insanity.

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pepe_mac t1_j8yqdsn wrote

First this study was funded by China, so a cynic might argue that they have a vested interest in discouraging sanctions. If you read the article the increase only represents 4.6 - 6% increase in costs. What undoubtedly has pushed people into poverty is the rise of food, yes, in part due to fuel, but mainly because of Russia's impeding Ukrainian grain and Russian fertilizer.

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TheThirdDumpling t1_j8ylchr wrote

Well, if you really care, you could put a retail price cap on the exported LNG for the good of humanity....

Btw, I know my gas and electricity doubled in price, and it's not Russia I am blaming.

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kellyasksthings t1_j8yilbf wrote

I read a historical novel once that had one character who was SA’d as a young girl and decided to become an anchorite both in penitence and self-protection - if you’re literally walled into a tiny room in a church then no one can get to you. Obviously that was all speculation, but I wonder how common it was?

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