Recent comments in /f/science

guystarthreepwood t1_j96tye4 wrote

Reply to comment by Appropriate_Banana in Pharmacological vitamin C inhibits mTOR signaling and tumor growth by degrading Rictor and inducing HMOX1 expression (Feb 2023) by basmwklz

Preface: it has been a minute since I studied these systems in detail, this is the jist of it. Vitamine c is a redox active molecule existing in an equilibrium between reduced and oxidized forms tending to favor the reduced form. Ascorbic acid (reduced vitamin c) gets oxidized by taking on a single electron from a radical (molecule with an unpaired electron) to form oxidized vitamin c. If it is exposed to oxygen or other oxidants for long periods of time it will exist largely in the oxidized form and end up being a prooxidant rather than antioxidant in order to re-establish the equilibrium. Your body is able to reduce oxidized vitamin c via various intracellular antioxidants (glutathione etc) but that initial exposure will produce some ROS.
Also in cell culture, there's often a high concentration of free iron floating around (5mM) which is totally unnatural. The free iron/vitamin c combo is able to create a Fenton reaction and produce huge amounts of ROS.

8

Kailaylia t1_j96txc2 wrote

Reply to comment by Amesenator in Pharmacological vitamin C inhibits mTOR signaling and tumor growth by degrading Rictor and inducing HMOX1 expression (Feb 2023) by basmwklz

>Liposomal-encapsulated Ascorbic Acid: Influence on Vitamin C Bioavailability and Capacity to Protect Against Ischemia–Reperfusion Injury
>
>The data indicate that oral delivery of 4 g of vitamin C encapsulated in liposomes produces circulating concentrations of vitamin C that are greater than unencapsulated oral but less than intravenous administration

8

Tempts t1_j96tkd9 wrote

Reply to comment by FartyPants69 in Reflexive fear responses tend to linger in people with anxiety disorders, study suggests by chrisdh79

That is just one part of a more robust post. And idk why you are focusing so much on that.

And this is vague because it has to be. There are professions that have many different rule sets they follow. Not everyone on Reddit is a 20 yr old boy. And not everyone on Reddit is without some level of reputation.

−17

PO0tyTng t1_j96t56j wrote

Reply to comment by Herbert-Quain in Scientists create carbon nanotubes out of plastic waste using an energy-efficient, low-cost, low-emissions process. Compared to commercial methods for carbon nanotube production that are being used right now, ours uses about 90% less energy and generates 90%-94% less carbon dioxide by Wagamaga

It’s not like nanotubes need to be made in 1000 gallon cauldrons. I would think we would need far less material than raw/smelted steel. So it could be made in a kiln or something. Honestly though the amount of heat needed is not a hurdle in scaling this up.

Really manually intensive /precise processes like making a sheet of graphene have soooo many more barriers to scaling than simply “apply more heat”

39

FartyPants69 t1_j96snr5 wrote

Reply to comment by Tempts in Reflexive fear responses tend to linger in people with anxiety disorders, study suggests by chrisdh79

I still don't understand what you're trying to say. You're saying you've met him and he said or did something bad to you personally?

I don't have a dog in the fight, I know nothing about the guy, but when you call someone a "terrible human being" I guess I think it's a good idea to be able to clearly articulate why

12

bernyzilla t1_j96s0nq wrote

Reply to comment by jackzander in Scientists have figured out a way to engineer wood to trap carbon dioxide through a potentially scalable, energy-efficient process that also makes the material stronger for use in construction by giuliomagnifico

Thank you. 2,000 tones is an insane amount. A quick Google search puts the weight closer to 20,000 pounds or ten tons.

Which will dramatically change the calculus for carbon sequestration. Also remember that this only works for new trees, and that mature forests release as much carbon as they absorb.

Still, I am all for planning as much trees as we can possibly get away with. Climate change is an emergency and we should be doing everything possible to mitigate it.

2

propaganda_bot-9733 t1_j96rk7f wrote

Reply to comment by ecksate in Scientists have figured out a way to engineer wood to trap carbon dioxide through a potentially scalable, energy-efficient process that also makes the material stronger for use in construction by giuliomagnifico

Concrete is not even close to the number one source of carbon emissions. It accounts for roughly 3% of total emissions, which is about 1/4 the amount that road transportation emits.

If we stopped using concrete completely, alone this action would have pretty much no measurable effect on our C02 problem. Although it could be part of the mosaic of solutions and that is worth saying.

1