Recent comments in /f/science

AutoModerator t1_j9wd8tz wrote

Reply to New cohort study of 3.7 million adults finds that long-term exposure to air pollution is associated with an increased risk of having a heart attack or dying from heart disease — associations more pronounced in low socioeconomic status communities by marketrent

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AutoModerator t1_j9wcasf wrote

Reply to ALMA confirmation of an obscured hyperluminous radio-loud AGN at z = 6.853 associated with a dusty starburst in the 1.5 deg2 COSMOS field | Monthly Notices of the Royal Astronomical Society by aivonette

Welcome to r/science! This is a heavily moderated subreddit in order to keep the discussion on science. However, we recognize that many people want to discuss how they feel the research relates to their own personal lives, so to give people a space to do that, personal anecdotes are allowed as responses to this comment. Any anecdotal comments elsewhere in the discussion will be removed and our normal comment rules apply to all other comments.

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Tob3n t1_j9w17qq wrote

Reply to Researchers have found the genetic links between headaches, migraines and blood sugar levels, which ultimately could lead to targeted treatments for patients by giuliomagnifico

So most of mine are preservative trigger nitrate/trites and more so sulfite/fates. Stimulation and fatigue are others. I made a correlation between seizures and migraines a decade ago but wasn’t sure how I came across it. Round 2018 anti seizure meds moved to 3rd in hierarchy for trial medication. Now including monoclonal antibodies that works on the seizure protein. CGRP

So what am I doing recently. Ketogenic diet, ya know, the real one developed for seizures. Since monoclonal treatment only offers a 33% reduction in frequency that’s all I have to beat. Still tracking in the long term at the moment but I have dodged at least 3 so far in the first month as I was slipping to ketosis.

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ProteinStain t1_j9vutzm wrote

Reply to comment by rbkc12345 in Researchers have found the genetic links between headaches, migraines and blood sugar levels, which ultimately could lead to targeted treatments for patients by giuliomagnifico

So, from reading it's clear that they are only just scratching the surface of the genetic correlation.
You are absolutely correct in that migraines are caused by many different factors, the glyaecemic connection they found is just one of them.

I know for me drinking water pretty much all day (not excessive amounts, but just being sure I'm drinking it all day long) has had a massive impact on reducing my migraines.

So ya, the article is only really talking about this food/blood sugar connection, and this is simply more data that will help those who suffer from migraines with those types of triggers.

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BagOFrogs t1_j9vtghk wrote

Reply to Researchers have found the genetic links between headaches, migraines and blood sugar levels, which ultimately could lead to targeted treatments for patients by giuliomagnifico

I get migraines. I also have (non-medical) issues with blood sugar - I get quite ill when my blood sugar gets low and this happens more easily compared with people I know. (However I don’t have symptoms of diabetes). Could this be part of the glycemic traits they’re referring to?

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eruborus t1_j9vrc1f wrote

Reply to comment by hippydog2 in Researchers have found that a Parkinson’s-linked mutation in a gene called Endophilin A1 blocks the process by which the body and the brain recycle cell waste. Without the process, autophagy, toxic debris builds up and neurons die. This discovery could change the focus of Parkinson's treatments. by QldBrainInst

It's research seeking to confirm a hypothesis. It needs to be replicated in mammalian cell line and then in an animal model. Drug development and clinical trials therafter. Bench to bedside in 15-20 years. Hard to say if is a breakthrough before that...ask the Alzheimers researchers.

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Apprehensive_Ad1744 t1_j9vpujw wrote

Reply to comment by accidental_snot in Researchers have found that a Parkinson’s-linked mutation in a gene called Endophilin A1 blocks the process by which the body and the brain recycle cell waste. Without the process, autophagy, toxic debris builds up and neurons die. This discovery could change the focus of Parkinson's treatments. by QldBrainInst

Atmospheric nitrogen just nitrogen, N2, which is relatively inert.

Nitrogen in exhaust are nitrogen oxides, namely NO and NO2, which are quite toxic.

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accidental_snot t1_j9vf290 wrote

Reply to comment by Darkhorseman81 in Researchers have found that a Parkinson’s-linked mutation in a gene called Endophilin A1 blocks the process by which the body and the brain recycle cell waste. Without the process, autophagy, toxic debris builds up and neurons die. This discovery could change the focus of Parkinson's treatments. by QldBrainInst

The earth's atmosphere is 80% nitrogen. What does it matter if it's in exhaust? Bonded with something to make some toxic molecule?

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arcum42 t1_j9vd7ev wrote

Reply to Companion robots to mitigate loneliness among older adults: "Most participants (68.7%) did not think an Artificial Companion robot would make them feel less lonely and felt somewhat-to-very uncomfortable (69.3%) with the idea of being allowed to believe that an artificial companion is human." by Gueulemer

Seems to me like if you can make it look realistically human where someone can't readily tell, you are taking the boring route and doing them a disservice by not telling them.

First off, if I know they aren't human, no reason to be embarrassed about the state of my apartment, or to feel guilty about having them cook and clean and basically do all the work around the place.

And if they can be realistically human, they could also be Klingon, an elf, a catgirl, a giant anthropomorphic bunny, or whatever I wanted, and this would undoubtedly be more entertaining...

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