Recent comments in /f/science

faiththeillustrious OP t1_j9zmp7x wrote

Reply to The Role of Insulin Signaling in Hippocampal-Related Diseases: A Focus on Alzheimer’s Disease by faiththeillustrious

Abstract highlights:

  • In recent years, more and more evidence has proved that insulin regulates various functions of the brain.
  • The hippocampus, one of the earliest brain regions affected by AD, is widely distributed with insulin receptors.
    • Studies have shown that type 2 diabetes mellitus, characterized by insulin resistance, is closely related to AD, which has drawn extensive attention to the relationship between hippocampal insulin signaling and AD.
  • We also highlight the molecular link between hippocampal insulin resistance and AD and provide a theoretical basis for finding new therapeutic targets for AD in clinical practice.
  • As a common link between T2DM and AD, in recent years, insulin resistance has been shown to contribute directly or indirectly to the progression of AD.
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RedditUser91805 t1_j9zmbna wrote

Reply to comment by ascandalia in For marginal occupations licensed by U.S. states, the welfare costs of licensing exceeds the benefits, as workers have to expend resources to obtain the license and consumers pay higher prices. [The study looks at professions that require license in some states but not others]. by smurfyjenkins

You inspired me to find out, so here are US states that do not require occupational licensing at the state level for:

Plumbers: Kansas, Missouri, Nebraska, Pennsylvania, and Wyoming

Electricians: Arizona, Florida, Illinois (except coal mine electricians), Indiana, Kansas, Maryland, Mississippi, Missouri, Nevada, New York, North Carolina, Pennsylvania, South Carolina

Contractors: Florida, Louisiana, Colorado, Connecticut, Kansas, Indiana, Kansas, Missouri, New Hampshire, New York, Ohio, Pennsylvania and Wyoming

Apparently Ontario de jure requires licenses, but hasn't been enforcing it, and therefore de facto doesn't.

Interesting!

More on topic, the data I had on mind but did not cite when I posted this comment was:

Kleiner, M. M., & Park, K. W. (2014, January). Life, limbs, and licensing: Occupational Regulation, wages ... Bureau of Labor statistics. Retrieved December 7, 2021, from https://www.bls.gov/opub/mlr/2014/article/pdf/life-limbs-and-licensing.pdf.

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Reply to The Role of Insulin Signaling in Hippocampal-Related Diseases: A Focus on Alzheimer’s Disease by faiththeillustrious

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LairdPopkin t1_j9zl06s wrote

Reply to comment by EconomistPunter in For marginal occupations licensed by U.S. states, the welfare costs of licensing exceeds the benefits, as workers have to expend resources to obtain the license and consumers pay higher prices. [The study looks at professions that require license in some states but not others]. by smurfyjenkins

Since the entire point of licensing is to drive up quality, because there is a harm to incompetent practitioners in many areas, it feels to me like the study is intentionally constructed to be misleading.

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bluddragon1 t1_j9zkv9z wrote

Reply to comment by kafelta in Workers tasked with moving products in the U.S. food and beverage supply chain are at a high risk of severe injuries and fatalities — Grocery wholesalers and grocery retail stores saw the highest number of injuries, followed closely by the warehousing and storage groups by marketrent

Somehow wage theft is bigger than all other types of theft, but I don’t ever see the people doing that arrested.

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ascandalia t1_j9zjv2z wrote

Reply to comment by RedditUser91805 in For marginal occupations licensed by U.S. states, the welfare costs of licensing exceeds the benefits, as workers have to expend resources to obtain the license and consumers pay higher prices. [The study looks at professions that require license in some states but not others]. by smurfyjenkins

The article only looks at marginal licensing in some states but not others. I doubt there's a state where plumbers, electricians and contractors aren't licensed.

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jnffinest96 t1_j9zjaxr wrote

Reply to comment by kafelta in Workers tasked with moving products in the U.S. food and beverage supply chain are at a high risk of severe injuries and fatalities — Grocery wholesalers and grocery retail stores saw the highest number of injuries, followed closely by the warehousing and storage groups by marketrent

Idk if its true but I heard walking across the street is more dangerous than being a police officer on a per minute basis

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themagicbong t1_j9zj1ee wrote

Reply to comment by 888mainfestnow in Workers tasked with moving products in the U.S. food and beverage supply chain are at a high risk of severe injuries and fatalities — Grocery wholesalers and grocery retail stores saw the highest number of injuries, followed closely by the warehousing and storage groups by marketrent

Even WITH drugs, if you ever talk to those kinds of people often you hear how many of them became addicts by taking their medication as prescribed. Like, as directed. Still ended up with a lovely lil opiate addiction as a result of something like even a workplace injury. Happened to me, I built my back very incorrectly from working wrong and got into painkillers. I've also seen that happen with guys I've worked with. Some people can maintain a functional life while spiraling down and it's not always that quick of a fall. Which can be like watching a trainwreck that began crashing a long ass time ago.

Then, while programs exist to get help at subsidized rates or even free of cost, they often don't seem to have great success rates for many reasons, chief among them being that the rules generally don't line up with medical science. They line up with whatever makes whoever is giving the money happy. Leads to situations where one day you go in to get your meds like you always do, but this time they say there's an issue. You see, you missed the group meeting, where everyone sits around swapping war stories about their times on drugs. Your doctor agrees that it's detrimental to your future sobriety, but you signed a contract stating you wouldn't miss group meetings. So even though you thought you'd be getting 30 days of medicine today, actually, you're getting nothing. Come back in a month to readmit into the program. If your doctor tries to intervene on your behalf, they might lose their medical license, and the clinic could have it's funding pulled.

Edit: just wanna say, that last situation I mentioned is how people die. I knew a woman who was in the same program I was in, and that exact scenario I described happened to both of us on the same day, and neither of us had ever so much as failed a piss test. I was luckily able to find another doctor and another program, but the woman wasn't as lucky, and she had overdosed by the end of the week.

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uberneoconcert t1_j9ziltg wrote

Reply to comment by b00basaurus in Researchers have found the genetic links between headaches, migraines and blood sugar levels, which ultimately could lead to targeted treatments for patients by giuliomagnifico

I personally feel a lot better when I'm eating more potatoes and no rice, only a handful of beans at a time. I did feel my best on keto but it's so difficult to maintain long-term and going back into ketosis once or twice a month so painful. Enjovy was the best migraine treatment for me. My migraine pain is constant rear tension and sensitive touch anywhere on the head.

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jeremyhat83 t1_j9zgmde wrote

Reply to comment by roberto1 in Workers tasked with moving products in the U.S. food and beverage supply chain are at a high risk of severe injuries and fatalities — Grocery wholesalers and grocery retail stores saw the highest number of injuries, followed closely by the warehousing and storage groups by marketrent

I was fired from a job and at the weekly meeting the owner told the employees to tell a lie if they were asked about why I was fired, to deny my unemployment claim. The issue was I confronted the owner for health and safety issues and he didn't want to spend a dollar on anything like that and wanted me to put people's lives at risk, and I wouldn't, and stopped him from teaching other employees that garbage

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Rndysasqatch t1_j9zg0on wrote

Reply to comment by binneysaurass in Workers tasked with moving products in the U.S. food and beverage supply chain are at a high risk of severe injuries and fatalities — Grocery wholesalers and grocery retail stores saw the highest number of injuries, followed closely by the warehousing and storage groups by marketrent

Yeah my father got screwed this way also. Spent the entire rest of his life fighting (there was a complication). I'll always remember how he had to fight tooth and nail. Anyway I feel you.

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D8NisOK t1_j9zftsz wrote

Reply to For marginal occupations licensed by U.S. states, the welfare costs of licensing exceeds the benefits, as workers have to expend resources to obtain the license and consumers pay higher prices. [The study looks at professions that require license in some states but not others]. by smurfyjenkins

I find licensing a pain in the ass... But is also a huge barrier of entry to my profession, so there's less competition and my fees reflect that.

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LClaypool2112 t1_j9zbqao wrote

Reply to comment by Algur in Workers tasked with moving products in the U.S. food and beverage supply chain are at a high risk of severe injuries and fatalities — Grocery wholesalers and grocery retail stores saw the highest number of injuries, followed closely by the warehousing and storage groups by marketrent

This is OSHA 1910.136. Nothing about steel toe boots being mandatory in a warehouse

“ General requirements. The employer shall ensure that each affected employee uses protective footwear when working in areas where there is a danger of foot injuries due to falling or rolling objects, or objects piercing the sole, or when the use of protective footwear will protect the affected employee from an electrical hazard, such as a static-discharge or electric-shock hazard, that remains after the employer takes other necessary protective measures.”

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Fakarie t1_j9zbavl wrote

Reply to comment by Algur in Workers tasked with moving products in the U.S. food and beverage supply chain are at a high risk of severe injuries and fatalities — Grocery wholesalers and grocery retail stores saw the highest number of injuries, followed closely by the warehousing and storage groups by marketrent

You posted: OSHA 1910.136 requires steel toe boots in a warehouse environment

What is actually says: The employer shall ensure that each affected employee uses protective footwear when working in areas where there is a danger of foot injuries due to falling or rolling objects, or objects piercing the sole, or when the use of protective footwear will protect the affected employee from an electrical hazard, such as a static-discharge or electric-shock hazard, that remains after the employer takes other necessary protective measures

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