Recent comments in /f/science
Ok-Cut4890 t1_jaq23fg wrote
Reply to comment by halebounddr in Anxiety can be created by the body, mouse heart study suggests by halebounddr
The anxiety is a secondary symptom of the IBS. I am a naturally very happy person. I have never done the beat myself up internal monologue. The anxiety I get is always very odd and difficult to understand why I suddenly got anxious. My life has always been very easy. I always finish tests first. Writing papers and math were always easy for me. I am always the golden boy at wherever I work. I've been offered free rides to grad school for my work performance. I easily command any conversation I care to.
Anxiety, insomnia, depression. These are things that should be obviously understood as a secondary symptom of something else.
Ok-Cut4890 t1_jaq1seh wrote
Reply to comment by ramkitty in Anxiety can be created by the body, mouse heart study suggests by halebounddr
My posture issues go away when my intestines are working properly. I will subconsciously bend to compress my upper colon area (where the rib cage ends). I have no problem with my posture when I'm taking my medication. So for me, bad posture is a secondary symptom of the IBS.
Ok-Cut4890 t1_jaq1hfa wrote
Reply to comment by MostStudiousMom in Anxiety can be created by the body, mouse heart study suggests by halebounddr
I discovered that I get insanely high blood pressure when I have some episodes, too. The IBS has only gotten more intense/severe as I've gotten older.
[deleted] t1_jaq00p1 wrote
Martholomeow t1_japuyh7 wrote
Reply to Scientists have successfully trialed new fully biodegradable and edible health sensors (such as those worn by runners or patients to monitor heart rate and temperature), built using natural elements like rock salt, water and seaweed, combined with graphene by giuliomagnifico
Ingesting graphene does not sound like a good idea
Meatrition OP t1_japt75k wrote
Reply to Long-Term Exposure to Isoflavones (genistein and daidzein) for 5 months Alters the Hormonal Steroid Homeostasis-Impairing Reproductive Function in Adult Male Wistar Rats by Meatrition
Abstract
The consumption of isoflavones is gaining popularity worldwide due to their beneficial effects on health. However, isoflavones are considered to be endocrine disruptors and cause deleterious effects on hormone-sensitive organs, especially in males. Therefore, this study aimed to determine if a continuous and prolonged exposure to isoflavones in adult males altered the endocrine axis effect of testicular function. For this purpose, seventy-five adult male rats were administered with low and high mixtures of isoflavones (genistein and daidzein) for 5 months. The determination of steroid hormones (progesterone, androstenedione, dehydroepiandrosterone, testosterone, dihydrotestosterone, 17β-estradiol, and estrone sulphate) was carried out in serum and testicular homogenate samples. Sperm quality parameters and testicular histology were also determined. The results revealed that low and high doses of isoflavones promote a hormonal imbalance in androgen and estrogen production, resulting in a decrease in circulating and testicular androgen levels and an increase in estrogen levels. These results are associated with a reduction in the sperm quality parameters and a reduction in the testicular weight, both in the diameter of the seminiferous tubules and the height of the germinal epithelium. Altogether, these results suggest that a continuous exposure to isoflavones in adult male rats causes a hormonal imbalance in the testes that disrupts the endocrine axis, causing defects in testicular function.
Meatrition OP t1_japt4t7 wrote
Reply to Long-Term Exposure to Isoflavones (genistein and daidzein) for 5 months Alters the Hormonal Steroid Homeostasis-Impairing Reproductive Function in Adult Male Wistar Rats by Meatrition
Introduction Genistein is an isoflavone phytoestrogen that induces cell differentiation in tissue culture Constantinou and Huberman (1995). An inhibitor of tyrosine kinase, histidine kinase, and topoisomerase Akiyama et al (1987), Huang et al (1992), Barnes and Petersen (1995), genistein is thought to be an anticancer, antiproliferative, cardioprotective and/or chemopreventive agent. It is possible, however, that the enzyme inhibitory effects may only occur at non-physiological concentrations Belenky et al (2003). At physiological concentrations, genistein activates the nuclear estrogen receptors ER-alpha and ER-beta Kuiper et al (1997), Kuiper et al (1998), Casanova et al (1999) and affects TGF-beta signaling pathways Kim et al (1998). While genistein, or its more soluble glucoside derivative genistin, are taken as a dietary supplement, they have not been thoroughly tested in clinical trials. Common dietary supplements often include other isoflavones, such as daidzein and glycitein or their corresponding glucoside conjugates.
AutoModerator t1_japsyuz wrote
Reply to Long-Term Exposure to Isoflavones (genistein and daidzein) for 5 months Alters the Hormonal Steroid Homeostasis-Impairing Reproductive Function in Adult Male Wistar Rats by Meatrition
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BumperCarcass t1_japsepl wrote
Reply to comment by Drixzor in Personal Psychedelic Use Is Common Among a Sample of Psychedelic Therapists: Implications for Research and Practice (Aday et al., 2023) by CmichPsychedelics
Right? Like unless they had ONE bad trip and thats now their entire perspective it seems like a positive thing they are familiar with the experience.
OpinionSorry1660 t1_japr8af wrote
Reply to A study found that "cannabis use is common amongst patients with tinnitus and current users of cannabis reported that it helped with their symptoms." by OregonTripleBeam
T for the last few years, never smoked anything but had the occasional ringing in my ears when I was younger. It was like somebody turned a tone generator up to 11 then it would fade out. Now it’s doesn’t fade out anymore and it sounds like cicadas, all the time.
Drixzor t1_japr4gn wrote
Reply to Personal Psychedelic Use Is Common Among a Sample of Psychedelic Therapists: Implications for Research and Practice (Aday et al., 2023) by CmichPsychedelics
I mean if you've every tried psychs in an even somewhat responsible manner this doesn't seem too surprising. Hell, I'd want my therapist to have tried psychs if they were hosting the therapy.
[deleted] t1_japqwtb wrote
Reply to comment by Admirable-Cabinet-52 in US public investment in critical research contributed to the success of mRNA Covid vaccines, and saved millions of lives by geoxol
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_OriamRiniDadelos_ t1_japqbmd wrote
Reply to comment by r-reading-my-comment in For the first time researchers have proven a clear correlation between deforestation and regional precipitation. by YoanB
An explanation of the Classic Maya collapse is that they deforested so much, over taxes their environment, and got hit by even harsher droughts because if it (Yucatán is not a land of rivers) so that’s why the mountain cities carried on and most the lowland ones suffered.
SpiritualJuice24 t1_jappgla wrote
Couldn’t results be based on the conscious reaction (fear, stress, confusion, concern) to one’s heart suddenly beating at an objectively different rate? I’m confused.
[deleted] t1_japp8q3 wrote
Reply to comment by halebounddr in Anxiety can be created by the body, mouse heart study suggests by halebounddr
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ktchong t1_japp7gz wrote
Reply to US public investment in critical research contributed to the success of mRNA Covid vaccines, and saved millions of lives by geoxol
Public investment. Private profit.
timespentwell t1_japno9c wrote
Reply to comment by PsychologicalLuck343 in Anxiety can be created by the body, mouse heart study suggests by halebounddr
I have anxiety even though my body can't make its own cortisol. I have to take hydrocortisone every day. (Addison's Disease)
So it must have other causes than too much cortisol.
Interesting to think about.
timespentwell t1_japnese wrote
Reply to comment by halebounddr in Anxiety can be created by the body, mouse heart study suggests by halebounddr
I had an increased heart rate (170s resting bpm) caused by right heart strain due to some problems caused by leftover PE(it never fully went away), and when I saw on the pulse ox how fast my heart was racing it induced a panic attack.
This has happened 3 times now.
[deleted] t1_japli28 wrote
NFT_goblin t1_japl09s wrote
There is comorbidity between anxiety, conditions like ADHD and autism, and also muscular/joint pain and joint hypermobility
Just some random google sources to show I'm not making it up:
ADHD and chronic pain: https://edgefoundation.org/adhd-and-chronic-pain/
ADHD, anxiety, and chronic pain are comorbitidies of autism: https://www.nhs.uk/conditions/autism/other-conditions/#:~:text=Problems%20with%20joints%20and%20other,that%20does%20not%20go%20away
Definitely think there is something to this. Anecdotally, I have anxiety, adhd, and also chronic pain that has really wrecked my life over the last few years. I hope some more productive research into this topic will be available soon.
[deleted] t1_japkhhu wrote
MostStudiousMom t1_japjysk wrote
Reply to comment by Ok-Cut4890 in Anxiety can be created by the body, mouse heart study suggests by halebounddr
I have IBD and I completely feel the same. I will get kind of a sinking feeling in my stomach like when you drop during a roller coaster ride, and then my heart rate will speed up and I'll start to sweat. I know that my stomach is about to show out and its time to pull out the antispasmodics.
[deleted] t1_japjhkk wrote
Carbon140 t1_japisyi wrote
Reply to comment by PsychologicalLuck343 in Anxiety can be created by the body, mouse heart study suggests by halebounddr
That's very kind. I don't really know if it's over the top to be concerned and it's obviously hard to tell the impact because it's so slow, but I definitely feel like it may be having an impact on me mentally from anxiety etc and also physically in the form of my body burning itself out faster than it needs to. I guess the easy weight control is convenient though. It's definitely frustrating to see something that looks like a problem in the future and have doctors seemingly take the attitude that they will do something about it once I have already fallen apart.
What sort of treatments are there? I know in my father's case his Thyriod overgrow in a nodular fation and when he got cancer the situation became much worse as he also had a wildly out of control heart. I remember him saying that he permanently had that feeling like someone had just popped a paper bag behind his head. If mine is overgrowing it would need surgery to remove part of it or some form of radiation iodine treatment to hamper it's function?
[deleted] t1_jaq25lg wrote
Reply to Long-Term Exposure to Isoflavones (genistein and daidzein) for 5 months Alters the Hormonal Steroid Homeostasis-Impairing Reproductive Function in Adult Male Wistar Rats by Meatrition
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