Wow I feel sorry for these mice.

> Here, to formally test this idea, we developed a noninvasive optogenetic pacemaker for precise, cell-type-specific control of cardiac rhythms of up to 900 beats per minute

Industry, academia and government should be and often are symbiotic in nature. The only ones opposed to this successful approach to invention and progress are conservatives who, as patsies to the elite rich, actively try to cut off funding to R&D in government and academia and send us backwards.

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Move to Australia

Absolutely true. One interesting overlap is with Prolapsed Mitral Valve, a common and usually mild heart abnormality, which can cause heart palpitations. A connection between people with PMV, panic disorder (PD) and hypermobility was notice many years ago. I'm once such example.

>The prevalence of MVP in PD and healthy controls was 27.20% and 9.21%, respectively. Patients with PD had a significantly increased relative risk of MVP compared to controls in the pooled sample (RR = 2.469, 95% confidence interval = 1.848–3.300). Age did not significantly modify the RR.

Also, I'm multiply cursed, ASD, ADHD, Prolapsed Mitral Valve, hypermobile joints, and panic attacks so bad in my teenage and early adulthood, that I could have represented my country at the panic attack Olympics. Thankfully I got over them.

Tural, U. and Iosifescu, D.V., 2019. The prevalence of mitral valve prolapse in panic disorder: a meta-analysis. Psychosomatics, 60(4), pp.393-401.

Garcia-Campayo, J., Asso, E. and Alda, M., 2011. Joint hypermobility and anxiety: the state of the art. Current Psychiatry Reports, 13, pp.18-25.

Tap your chest, block the sensation of your heart beating. If you feel self-conscious doing this in public, fold your arms and tap your chest without others noticing. It's a matter of breaking the positive feedback loop between pulse rate and anxiety. It's something I first did 20 years ago.

The word “contributed” implies that it wasn’t a solo effort.

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It being because of race isn't the same as it being because of racism, what are you on?

The problem you're ignoring here is that these companies are double dipping. They are funded by the government to research these new drugs AND are charging a huge amount for them. Pick one.

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I work in cancer research in the UK, and ALL our money is coming from the government. Where there's a will and relevant priorities, there's a way. That's really the crucial part, because governments have plenty of money to spend. Where they spend it is the real question, not how to raise more.

That said, even just moving the extracted profit into taxes instead would yield a substantial improvement. People make money off of this. Stop that and move the money back into research.

If the government wants to accelerate research it has to tax more. Its also getting less taxes from biotech/pharm companies because they cant make profit.

In order to bridge this gap the government needs to make money from somewhere (taxes) or no research will be funded.

The US government cannot print money forever without raising taxes.

Too bad that the reality of that theory is conglomerates eating up subsidies and then gouging us again for IP we've already paid for. There is no competition after capital accumulation has run its course and the legislative is captured by the few remaining monopolies.

Taxes aren't profit extraction and this idea that the profit motive is driving research is nonsense. Funding to conduct research is already taken from taxpayers.

Vaccination was free in Australia. I had 2 shots in late 2021 just so I could go to venues to be part of the darts team. I know a lot of people who refused any vaccinations. Does not matter now. I just ignored it and carried on regardless

HRV biofeedback therapy is already used for exactly this reason - as well as for IBS annd chronic pain among other physical conditions impacted by the autonomic nervous system and specifically the vagus nerve, as the discussion above also mentioned.

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We gave vitamin K agonists to rats to prevent clotting causing them to bleed out. Not vitamin D

This seems to suggest the James-Lange theory of emotions is true.

My heart has issues controlling rate, resting could be 60, could be 140. When it's elevated I feel anxiety before I check and know it's high, then knowing that it's elevated causes more anxiety which drives it even higher, fun. So I would say both can impact it.

Wait, taken from the taxpayers? We already pay this profit as taxpayers (as consumers and taxpayers) and multiples above what is needed. Most of the base research is publicly paid for.

Pharmaceutical companies will develop products based on a specific conception of this market. This is a different set of priorities than the state. Moreover, they actively work to influence doctors, hospitals, and in the US have nearly captured all legislators. Selling and marketing account for more or equal to research and development.

Freedom of research is questionable. What if a disease/condition targets a segment of the population that is less profitable/politically important? Or if a competitor made an erectile-dysfunction drug then all others companies have to compete due to lucrative market rather than other needs.

No wayyyyyyyyyyyyyyyyyyyyyyyyyyyyyyy