I can assure you, no tea is gonna make you feel like mdma does. Don’t be such a square.

Dude mda is great though.

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See my comments above, they basically have proven this. I am so glad that there is a major community of people these days who are using psychedelic therapy in the ways that it should be. Massive amounts of historical context provide validity to the value of psychedelic substances when they are used as you have used them. Again, I really appreciate you pointing out that these substances don't "need" to be used in a prescriptive sense. Rather, prescriptive power should be used to help ensure the substances are given validity, as well as to ensure they are not used excessively (this abuse rarely happens as there is significant evidence to show they are not even remotely addictiveaddictive )

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Not many apes around for proper virus evolution makes me question this

Doesn't even need to infect humans to harm us.

Most of our food supply depends on just a few species of plants.

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I’m betting it differs from person to person. I found it very helpful since no medications helped.

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I never said it wasn't questionable benefit to many people, I explicitly said that. We can cite study after study or meta-analysis after meta-anaylsis, but the fact is, SSRIs score above placebo in statistical significance more often than not, opinion on them notwithstanding. I work in I guess tangent to the field of epidemiology, but I write software for use by epidemiologists for after market drug effect statistical analysis, on algorithms we use to do that. SSRIs are well above placebo, doesn't matter whether you can cite criticism of them or not, and non-SSRI antidepressants almost all work on the serotoninergic system to some level. Ketamine and bupropion are examples that don't directly, or ketamine at all, but ketamine's MOA is not fully understood beyond that we believe the neuroplasticity change to be significant. Ketamine's acute antidepressant effects last well beyond the length of the drug or known medically relevant metabolites being in your system.

Unfortunately, people who had bad experience with SSRIs really love to make that known even if they know barely beyond an iota of knowledge in the actual science. Even if this is /r/science. And it's really frustrating.

how come no ssri?

you ever had that nice amber rock?

I can only imagine how stupid you are and I hope you find genius over night.i would encourage anything but hard-core substances. Try first, herbal teas from etsy, blue lotus flower, weed edibles, natural things ect.

I will confirm. SSRIs did everything but improve my quality of life. In fact, all my physical issues got worse which in turn made my psychological go into silent hill mode, fog and everything.

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I was diagnosed with mood disorders and was on western medicine for years until I discovered LSD….now I do 2 trips a year where I center myself 0ver a weekend and I have not needed my mood disorder medicine…

From my perspective, this works amazingly well…I can’t wait till the studies prove this all out.

"Positive Expiratory Pressure" device - you can also accomplish this using a straw, pinching it slightly so you have to force the air out as you blow.

Mdma is the good stuff. Much Molly for sale contains Methamphetamine. Mixed with MDMA. And sometimes MDA.
But pure MDMA is The Best.

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Look into a company called Mind Medicine. They are doing amazing work regarding this topic.

Yeah, and being convinced is a big and important step for sure. I only meant to reassure that it is almost certainly far easier than you're imagining.

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Flaminate was likely referring to :

More that studies have shown that after decades, there is still no evidence that depression is caused by low seratonin levels https://www.sciencedaily.com/releases/2022/07/220720080145.htm

That anti-depressants have questionable benefit to a significant number of patients.

> Antidepressants seem to have minimal beneficial effects on depressive symptoms and increase the risk of both serious and non-serious adverse events -- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418603/

Meta-studies showing that SSRI use was not beneficial in the long term. (Not beneficial as in harmful to long-term health)

> Outcome reporting was less thorough during follow-up than for the intervention period and only two trials maintained the blind during follow-up. All authors concluded that the drugs were not beneficial in the long term. -- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839490/

-- I agree on the Ketamine and Psychedelics.

Ketamine treatment has done wonders for myself, and several of my friends.

https://www.health.harvard.edu/diseases-and-conditions/the-gut-brain-connection

I’ll just leave this for you to read. All mental stuff is far more than serotonin as we are currently learning.