Recent comments in /f/science

gadget850 t1_jbzt27p wrote

Reply to comment by lorrie_101 in New information about the role of a molecule found in chillis in reducing foot pain by healing damaged nerves. After three months, the team found that those who’d been treated with the capsaicin patch reported that their pain had reduced significantly, compared to those treated with standard care by Wagamaga

I've been looking. The patches in the article are 8% and prescription. Every patch and cream I have found OTC is 0.025%.

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astern126349 t1_jbzrw2s wrote

Reply to comment by jdippey in New information about the role of a molecule found in chillis in reducing foot pain by healing damaged nerves. After three months, the team found that those who’d been treated with the capsaicin patch reported that their pain had reduced significantly, compared to those treated with standard care by Wagamaga

This may sound dumb…can you use the patches on your feet for neuropathy? I would think the cream would work better.

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Papancasudani t1_jbzrb72 wrote

Reply to comment by kinda_alone in New information about the role of a molecule found in chillis in reducing foot pain by healing damaged nerves. After three months, the team found that those who’d been treated with the capsaicin patch reported that their pain had reduced significantly, compared to those treated with standard care by Wagamaga

Tangential to what you said, it actually san't be placebo tested because there's no burning inactive placebo. If something doesn't burn then it can be distinguished from the actual treatment, which makes it useless as a placebo. If it burns, it's probably activating the same channels as capsaicin does, in which case it's not inactive.

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gratusin t1_jbzqxix wrote

Reply to comment by Skaindire in New information about the role of a molecule found in chillis in reducing foot pain by healing damaged nerves. After three months, the team found that those who’d been treated with the capsaicin patch reported that their pain had reduced significantly, compared to those treated with standard care by Wagamaga

I eat some form of chile pretty much everyday. I have never had foot pain, but if I go overboard… boy does another part of my body feel it.

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jdippey t1_jbzp38y wrote

Reply to comment by Skaindire in New information about the role of a molecule found in chillis in reducing foot pain by healing damaged nerves. After three months, the team found that those who’d been treated with the capsaicin patch reported that their pain had reduced significantly, compared to those treated with standard care by Wagamaga

Not in this study, but I’m sure you can find other studies which tested different administration methods and found equivocal results.

Eating capsaicin just isn’t the best method to get the desired reductions in neuropathic pain. Eating more hot peppers will not help diabetics with such symptoms.

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Skaindire t1_jbzolm3 wrote

Reply to comment by jdippey in New information about the role of a molecule found in chillis in reducing foot pain by healing damaged nerves. After three months, the team found that those who’d been treated with the capsaicin patch reported that their pain had reduced significantly, compared to those treated with standard care by Wagamaga

Has not been tested for either. They specifically tested the patch and nothing else. It's

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Man_Bear_Beaver t1_jbznhc9 wrote

Reply to New information about the role of a molecule found in chillis in reducing foot pain by healing damaged nerves. After three months, the team found that those who’d been treated with the capsaicin patch reported that their pain had reduced significantly, compared to those treated with standard care by Wagamaga

I use capsaicin cream for my knees, it’s the best thing I’ve ever found for them

I once rubbed my eyes after applying it, not very fun.

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jdippey t1_jbzmy2h wrote

Reply to comment by Skaindire in New information about the role of a molecule found in chillis in reducing foot pain by healing damaged nerves. After three months, the team found that those who’d been treated with the capsaicin patch reported that their pain had reduced significantly, compared to those treated with standard care by Wagamaga

Capsaicin patches (topical administration) were used in this study. Consuming peppers has not been shown to reduce peripheral neuropathy.

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ModsAreN0tGoodPeople t1_jbzgg9w wrote

Reply to comment by oooshi in MDMA appears to confer resilience in a rodent model of chronic social defeat stress by chrisdh79

You end up with low serotonin because Molly basically tells your brain to just dump it all into your bloodstream. I personally never experienced the “hangover” effect , had a very nice afterglow after the high wore off and was right as rain next day but everybody is different. The one thing to avoid is trying to do it again too quickly. I limited my self to once a month otherwise the trip wasn’t very strong.

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noechtwoow t1_jbzeq74 wrote

Reply to comment by wildfire98 in University of Virginia scientists have identified a calorie-restriction pathway that extends the lifespan of worms and yeast by reducing levels of glycerol. by shadesofaltruism

The point of the paper itself is not that “decreasing toxic byproducts of fat could make you feel better and live longer” but that the increased expression of adh-1 (which was not known to play a role in clearing byproducts of fat metabolism afaik) is sufficient and necessary to extend lifespan

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lorrie_101 t1_jbzcga2 wrote

Reply to New information about the role of a molecule found in chillis in reducing foot pain by healing damaged nerves. After three months, the team found that those who’d been treated with the capsaicin patch reported that their pain had reduced significantly, compared to those treated with standard care by Wagamaga

WOW!! First time I'm learning about this!! I don't have diabetes, but have arthritis in both feet (for the last +/- 15 years)...I'm relatively young, & have never understood how this happened (tho I used to run 5 - 7 miles/day, 7 days/week, & figured that's why.) It literally feels like the bones in my feet are broken shards of glass walking on metal ballbearings. I can't wait to try this! Pain has def increased since being on chemo for Leukemia. Are these patches available at local drugstores? Do you need a prescription, or are they over-the-counter (in USA)? I will def discuss w my Hematologist/Oncologist. Thank you, all, for taking the time to post, comment, & for your contributions.

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Betadzen t1_jbzbz9l wrote

Reply to comment by DisplayPorts in New information about the role of a molecule found in chillis in reducing foot pain by healing damaged nerves. After three months, the team found that those who’d been treated with the capsaicin patch reported that their pain had reduced significantly, compared to those treated with standard care by Wagamaga

Shows his own patches.

Trust me, this won't be painless. Also I strongly suppose that this research was conducted by a team of crocodiles that wanted humans under the hot sauce.

But, well, better than nothing.

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