Recent comments in /f/science

quantumgpt t1_jc13iqm wrote

I ..I ..... Might love you.

I've changed my entire life and improved my fitness. With one damn problem. I have nerve pain in my left foot. I'm in reasonable shape and even do barefoot running on the beach at times. But currently. I'm up tapping my foot trying to shake the pain away. I'll be making my own patches if I can't find any with a similar percentage. If this works..... It would be incredible. I've been trying to fight and hide this for a year and a half now. 80lbs down. Major improvements. But not on the damn foot.

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lorrie_101 t1_jc12vsp wrote

Wow! Thank you, so very much, for your response.

I do have pain all over - joints, tendons, muscles, & large bones - feet are the worst. I received my Leukemia (CML) diagnosis 5 yrs ago...My Hem-Onc specialist @ UCSF told me at diagnosis I'd had it for the prior 10~12 years (so 15~17 years, since age 38~40.) I'm on my 4th regimen; it's new. Despite the pain, I'm thankful to be alive, especially for my kids...20 years ago, I'd have been dead 2 months after diagnosis.

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BiochemistChef t1_jc11wv2 wrote

What was the "warmer temperature" the news release talked about. Not having to fill the spectrometer with liquid He (or even just less often, as well as the N2) would be great

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BafangFan t1_jc10qqc wrote

Going on the carnivore diet has helped my aches and pains more than anything I could have imagined.

I've been eating crap food again lately, and it feels like I've aged 10 years in the span of 1 month

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redrightreturning t1_jc0ubqc wrote

Nurse here… Chemo can cause nerve pain. Talk to the provider who is ordering your chemo and get a prescription for capsaicin patches. I think they are certainly worth a try, and very low risk.

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AoedeSong t1_jc0qwcr wrote

Capsaicin drops became my go to for sore throat treatment, it has helped me tremendously… after Covid the sore throat caused this ongoing involuntary coughing spasms long after the original Covid infection had resolved. But it would trigger with a laugh or just talking or breathing too hard and it was so painful from the constant irritation - I remembered how capsaicin drops had helped my throat in the past and I still had a bottle, I was so surprised how it also stopped the coughing spasms and helped my throat heal up. Seemed so counter intuitive that capsaicin would help sore throat & throat irritation but here we are.

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Technical_Sir_9588 t1_jc0mgo4 wrote

The prior study that I read about used 8% patches so they had to anesthetize the area prior to application. The over the counter roll on from CVS is 0.15% and that burns hot enough.

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Technical_Sir_9588 t1_jc0m60m wrote

The interesting thing is that I learned about this from a similar study probably about 6-7 years ago. Capsaicin damages the mitochondria in sensitized nerve cells (which are currently dysfunctional due to sending information to the brain that is incorrect). After the capsaicin application, the nerve cells first retract to some degree from the tissue they're inervating (such as the skin). Eventually those nerve cells regrow but apparently without dysfunctional signaling. I work in health care and I'm always looking for options to help my patients, especially those with chronic pain. I've never found a practitioner that utilized the capsaicin approach. If any, I would expect physiatrists to be the most open-minded to utilize this as a treatment option.

Edit.

This may be the study: https://openaccesspub.org/article/549/ijp-17-1581.pdf

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