Recent comments in /f/singularity

DungeonsAndDradis t1_j6fy0be wrote

Yeah, I do the $49.99 monthly subscription. It lets me access up to 15 subreddits, and I can give out 150 upvotes, and 25 downvotes. I'm also allowed to post up to 10 submissions a month, and comment 100 times. This comment is costing me something like 7 cents. They don't really break it down by "each submission costs x" or "each upvote costs x". It's all rolled into the monthly fee.

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Verzingetorix t1_j6fxl53 wrote

Yes, but AI exists already and has been in use in biomedical research for a while. In-silico clinical trials does not.

We can speculate about the first, but not how the first will do in light of the second. Especially when we would have to also come up with a reasonable argument on how would simulated trials even get approved.

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Verzingetorix t1_j6fx0os wrote

People decide for themselves. During patient recruitment there's an informative phase.

The patients who are interested in participating, and meet the eligibility criteria, have to be informed about the risks. That's meant to fulfill the informed consent requirements.

Many candidates choose not to move forward based on the risks. Or if they did enrolled, if other patients have poor outcomes or adverse incidents, or if they personally don't see improvements they can drop out.

Also, some patients just die, or have secondary health incidents that force them to cease their participation.

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pre-DrChad t1_j6fu13g wrote

That’s pretty much what this sub is. We are all speculating what AI will do in the future. Do you believe the singularity is possible? If so, it’s an odd statement to make that therapies won’t be approved based on simulated trials. I doubt the FDA or any such regulatory bodies will even exist in the future. What’s the need for human regulations when we have super intelligence far beyond our own?

We already have organ on a chip models, so we already have the building blocks for simulating a human. At the point where trials on a simulated human can predict results as well as human clinical trials, I bet we stop using human clinical trials.

Since you work on human clinical trials, you would know that humans are very diverse and not every human responds the same way to a treatment. So it’s not like human clinical trials are even close to perfect. We can use technology to move past human clinical trials

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Smellz_Of_Elderberry OP t1_j6ftmsn wrote

Good points.

I just don't get why people aren't able to take greater risks, like say you have a terminal illness? Why not let people decide for themselves? I feel like I would want to take greater risks.

Also, we saw a whole new kind of vaccine get released in record time. Why isn't this kind of speed possible with other kinds of drugs?

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SurroundSwimming3494 t1_j6fs04j wrote

I mean, they can of course be biased, but at the end of the day they know the most about what their jobs entail and how easy/hard it is to automate certain programming tasks, not to mention that some are also at least somewhat familiar with AI, which makes their answers more credible.

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